铜绿假单胞菌对细胞介导免疫反应的损害。
Impairment of cell-mediated immune responses by Pseudomonas aeruginosa.
作者信息
Floersheim G L, Hopff W H, Gasser M, Bucher K
出版信息
Clin Exp Immunol. 1971 Aug;9(2):241-7.
Abstract
A lyophilizate from inhibits markedly the tuberculin reaction in guinea-pigs. This property is shared with products of other Gramnegative bacteria. The latter display, however, no clear cut effect on the homograft reaction. In contrast, prolonged skin homograft survival in mice. The effect was dose-dependent. Quantitative considerations suggest that produces an immunosuppressive substance of outstanding activity.
摘要
来自……的冻干制剂能显著抑制豚鼠的结核菌素反应。其他革兰氏阴性菌的产物也有这种特性。然而，后者对同种移植反应没有明显作用。相比之下，……能延长小鼠皮肤同种移植的存活时间。这种作用呈剂量依赖性。从定量角度考虑表明，……产生了一种活性极强的免疫抑制物质。
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