酰基木瓜蛋白酶反应的动力学和热力学。pH值、温度、溶剂、离子强度及添加亲核试剂的影响。 - Suppr | 超能文献

Kinetics and thermodynamics of the reactions of acyl-papains. Effects of pH, temperature, solvents, ionic strength, and added nucleophiles.

作者信息

Hindle P M, Kirsch J F

出版信息

Biochemistry. 1971 Sep 28;10(20):3700-7. doi: 10.1021/bi00796a010.

DOI:10.1021/bi00796a010

Abstract

摘要

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引用本文的文献

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Clarification of the pH-dependent kinetic behaviour of papain by using reactivity probes and analysis of alkylation and catalysed acylation reactions in terms of multihydronic state models: implications for electrostatics calculations and interpretation of the consequences of site-specific mutations such as Asp-158-Asn and Asp-158-Glu.利用反应性探针阐明木瓜蛋白酶的pH依赖性动力学行为，并根据多质子态模型分析烷基化和催化酰化反应：对静电计算以及对位点特异性突变（如Asp-158-Asn和Asp-158-Glu）后果的解释的意义。

Biochem J. 1993 Aug 15;294 ( Pt 1)(Pt 1):201-10. doi: 10.1042/bj2940201.