合成促甲状腺激素释放因子（TRF）类似物。II. 焦谷氨酸-N3-咪唑甲基组氨酸-脯氨酸-氨基：一种比TRF2具有更高比活性的合成类似物。 - Suppr

Suppr

超能文献

Synthetic TRF (thyrotropin releasing factor) analogues. II. pGlu-N3imMe-His-Pro-NH2: a synthetic analogue with specific activity greater than that of TRF2.

作者信息

Vale W, Rivier J, Burgus R

出版信息

Endocrinology. 1971 Dec;89(6):1485-8. doi: 10.1210/endo-89-6-1485.

DOI:10.1210/endo-89-6-1485

PMID:5001013

Abstract

摘要

相似文献

Synthetic TRF (thyrotropin releasing factor) analogues. II. pGlu-N3imMe-His-Pro-NH2: a synthetic analogue with specific activity greater than that of TRF2.合成促甲状腺激素释放因子（TRF）类似物。II. 焦谷氨酸-N3-咪唑甲基组氨酸-脯氨酸-氨基：一种比TRF2具有更高比活性的合成类似物。

Endocrinology. 1971 Dec;89(6):1485-8. doi: 10.1210/endo-89-6-1485.

[Biological action of synthetic hypothalamic hormone TRF (thyrotropin-releasing factor). 1. Effect of synthetic TRF in vivo and in vitro].[合成下丘脑激素TRF（促甲状腺激素释放因子）的生物学作用。1. 合成TRF在体内和体外的作用]

Nihon Naibunpi Gakkai Zasshi. 1970 Oct 20;46(7):821-5. doi: 10.1507/endocrine1927.46.7_821.

Porcine thyrotropin releasing hormone is (pyro)glu-his-pro(NH2).猪促甲状腺激素释放激素为（焦）谷氨酰-组氨酰-脯氨酰胺。

Endocrinology. 1970 May;86(5):1143-53. doi: 10.1210/endo-86-5-1143.

In vitro studies with thyrotropin releasing factor.促甲状腺素释放因子的体外研究。

Rev Neuropsychiatr Infant. 1966 Dec;14(12):320-5. doi: 10.3181/00379727-126-32436.

Thyrotropin releasing hormone and its analogues I. New syntheses and biological properties of TRH (Pro-NH-NH2)3-TRH and (2-Picolyl)-TRH.促甲状腺激素释放激素及其类似物I. （脯氨酰胺基）₃-促甲状腺激素释放激素和（2-吡啶甲基）-促甲状腺激素释放激素的新合成方法及生物学特性

Mater Med Pol. 1980 Jan-Jun;12(1-2):129-35.

[Biological activity of synthetic thyrotropin releasing factor].[合成促甲状腺素释放因子的生物活性]

Probl Endokrinol (Mosk). 1973 May-Jun;19(3):50-2.

[Biological action of synthetic hypothalamic hormone TRF (thyrortropin-releasing factor). 2. Specificity and modifying factor of synthetic of biological action of TRF].[合成下丘脑激素TRF（促甲状腺素释放因子）的生物学作用。2. TRF生物学作用合成的特异性及修饰因子]

Nihon Naibunpi Gakkai Zasshi. 1970 Oct 20;46(7):826-9.

Biological activity of synthetic polypeptide derivatives related to the structure of hypothalamic TRF.与下丘脑促甲状腺素释放因子结构相关的合成多肽衍生物的生物活性

Endocrinology. 1970 Mar;86(3):573-82. doi: 10.1210/endo-86-3-573.

Stimulation of 14-C-glucosamine and 14-C-alanine incorporation into thyrotropin by synthetic thyrotropin-releasing hormone.合成促甲状腺激素释放激素对14-C-葡萄糖胺和14-C-丙氨酸掺入促甲状腺激素的刺激作用。

Endocrinology. 1971 Sep;89(3):873-7. doi: 10.1210/endo-89-3-873.

Prolactin release in vitro and in vivo in the pigeon and the domestic fowl following administration of synthetic thyrotrophin-releasing factor (TRF).给予合成促甲状腺素释放因子（TRF）后家鸽和家鸡体内外催乳素的释放情况

Gen Comp Endocrinol. 1975 Mar;25(3):298-306. doi: 10.1016/0016-6480(75)90119-7.

引用本文的文献

Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{-[(4,5)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-l-alanyl}-(2)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate).口服有效的促甲状腺激素释放激素模拟物的发现：1-{[(4,5)-(5-甲基-2-氧代恶唑烷-4-基)羰基]-3-(噻唑-4-基)-L-丙氨酰}-(2)-2-甲基吡咯烷三水合物（罗伐瑞林水合物）

ACS Omega. 2018 Oct 31;3(10):13647-13666. doi: 10.1021/acsomega.8b01481. Epub 2018 Oct 19.

Corticotropin-releasing factor peptide antagonists: design, characterization and potential clinical relevance.促肾上腺皮质素释放因子肽拮抗剂：设计、表征及潜在临床相关性。

Front Neuroendocrinol. 2014 Apr;35(2):161-70. doi: 10.1016/j.yfrne.2013.10.006. Epub 2013 Nov 20.

Inverse agonist abolishes desensitization of a constitutively active mutant of thyrotropin-releasing hormone receptor: role of cellular calcium and protein kinase C.反向激动剂消除促甲状腺激素释放激素受体组成型活性突变体的脱敏：细胞钙和蛋白激酶C的作用

Br J Pharmacol. 1999 Mar;126(5):1097-106. doi: 10.1038/sj.bjp.0702415.

[Stimulation of TSH secfetion by TRF load in hypothalamic and pituitary diseases].[下丘脑和垂体疾病中TRF负荷对促甲状腺激素分泌的刺激作用]

Klin Wochenschr. 1972 Jan 1;50(1):42-52. doi: 10.1007/BF01487775.

Modulation of GABA-gated chloride currents by intracellular Ca2+ in cultured porcine melanotrophs.细胞内钙离子对培养的猪促黑素细胞中γ-氨基丁酸门控氯离子电流的调节作用

J Physiol. 1991 Jun;437:109-32. doi: 10.1113/jphysiol.1991.sp018587.

Direct effects of protirelin (TRH) on cultured porcine thyrocytes.促甲状腺素释放激素（TRH）对培养的猪甲状腺细胞的直接作用。

J Endocrinol Invest. 1992 May;15(5):345-51. doi: 10.1007/BF03348750.

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