Thyrotropin releasing hormone and its analogues I. New syntheses and biological properties of TRH (Pro-NH-NH2)3-TRH and (2-Picolyl)-TRH.
作者信息
Bobrowska J, Leroux P, Maliński E, Przybylski J, Szafranek J, Tonon M C, Vaudry H, Kupryszewski G
出版信息
Mater Med Pol. 1980 Jan-Jun;12(1-2):129-35.
PMID:6799704
Abstract
摘要
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[Proceedings: Various factors influencing pituitary TSH release in rats. 2. Effects of synthetic TRH and its analogues].[会议论文：影响大鼠垂体促甲状腺激素释放的各种因素。2. 合成促甲状腺激素释放激素及其类似物的作用]
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Release of thyrotropin and prolactin by a thyrotropin-releasing hormone (TRH) precursor, TRH-Gly: conversion to TRH is sufficient for in vivo effects.促甲状腺激素释放激素（TRH）前体TRH-Gly对促甲状腺激素和催乳素的释放作用：转化为TRH足以产生体内效应。
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TRH analogue with C-terminal thioamide group. Synthesis, receptor binding, TSH-releasing activity and alpha-MSH-releasing activity.具有C端硫代酰胺基团的促甲状腺激素释放激素类似物。合成、受体结合、促甲状腺激素释放活性及α-促黑素细胞激素释放活性
Experientia. 1985 Dec 15;41(12):1576-7. doi: 10.1007/BF01964815.
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Inhibition of p-chlorophenylalanine-induced muricide behavior following TRH microinjection into the limbic structures in the rat.向大鼠边缘结构微量注射促甲状腺激素释放激素（TRH）后对氯苯丙氨酸诱导的杀鼠行为的抑制作用
J Neural Transm. 1988;74(3):175-80. doi: 10.1007/BF01244783.
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