切牙牙髓细胞体外合成前胶原

Synthesis of procollagen by dental pulp cells from incisor in vitro.

作者信息

Gotoh Y, Saito S, Sato A

出版信息

J Biochem. 1979 Oct;86(4):1037-40. doi: 10.1093/oxfordjournals.jbchem.a132597.

DOI:10.1093/oxfordjournals.jbchem.a132597

Abstract

Fibroblast-like cells were isolated from dental pulp of rabbit incisor, and were shown to synthesize and secrete procollagen. Analysis of the secreted procollagen and their CNBr peptides indicated that the prominent form was type I procollagen. Our results also suggested the presence of type III procollagen as a minor component synthesized by pulp cells in vitro.

摘要

从兔切牙牙髓中分离出成纤维样细胞，这些细胞可合成并分泌前胶原。对分泌的前胶原及其溴化氰肽段的分析表明，主要形式为I型前胶原。我们的结果还提示，III型前胶原作为牙髓细胞体外合成的次要成分也存在。