• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation.

作者信息

Okey A B, Bondy G P, Mason M E, Kahl G F, Eisen H J, Guenthner T M, Nebert D W

出版信息

J Biol Chem. 1979 Nov 25;254(22):11636-48.

PMID:500663
Abstract
摘要

相似文献

1
Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation.
J Biol Chem. 1979 Nov 25;254(22):11636-48.
2
Nuclear uptake of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6J and DBA/2J mice. Role of the hepatic cytosol receptor protein.2,3,7,8-四氯二苯并对二恶英在C57BL/6J和DBA/2J小鼠中的核摄取。肝细胞溶质受体蛋白的作用。
J Biol Chem. 1979 Oct 10;254(19):9814-21.
3
Regulatory gene product of the Ah complex. Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene binding to several moieties in mouse liver cytosol.芳烃(Ah)复合物的调节基因产物。2,3,7,8-四氯二苯并对二恶英和3-甲基胆蒽与小鼠肝脏胞质溶胶中多个部分结合的比较。
J Biol Chem. 1981 May 10;256(9):4584-90.
4
Characterization of multiple forms of the Ah receptor: comparison of species and tissues.芳烃受体多种形式的特性:物种与组织的比较
Biochemistry. 1989 Jul 25;28(15):6430-40. doi: 10.1021/bi00441a041.
5
Cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Evidence for a homologous nature among various mammalian species.2,3,7,8-四氯二苯并对二恶英的胞质受体。不同哺乳动物物种间同源性的证据。
Mol Pharmacol. 1984 Jul;26(1):90-8.
6
Detection and characterization of a low affinity form of cytosolic Ah receptor in livers of mice nonresponsive to induction of cytochrome P1-450 by 3-methylcholanthrene.对3-甲基胆蒽诱导细胞色素P1-450无反应的小鼠肝脏中一种低亲和力胞质型芳烃受体的检测与特性分析。
Mol Pharmacol. 1989 Jun;35(6):823-30.
7
Ah receptor in mice genetically "nonresponsive" for cytochrome P4501A1 induction: cytosolic Ah receptor, transformation to the nuclear binding state, and induction of aryl hydrocarbon hydroxylase by halogenated and nonhalogenated aromatic hydrocarbons in embryonic tissues and cells.对细胞色素P4501A1诱导具有基因“无反应性”的小鼠中的芳烃受体:胞质芳烃受体、向核结合状态的转变以及胚胎组织和细胞中卤代和非卤代芳烃对芳烃羟化酶的诱导。
Mol Pharmacol. 1991 Nov;40(5):818-26.
8
2,3,7,8-Tetrachlorodibenzo-p-dioxin induces the nuclear translocation of two XRE binding proteins in mice.2,3,7,8-四氯二苯并对二恶英诱导小鼠体内两种XRE结合蛋白的核转位。
Pharmacogenetics. 1993 Apr;3(2):101-9. doi: 10.1097/00008571-199304000-00006.
9
Cytosolic and nuclear binding proteins for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat thymus.大鼠胸腺中2,3,7,8-四氯二苯并对二噁英的胞质和核结合蛋白
Biochim Biophys Acta. 1982 May 5;716(1):16-23. doi: 10.1016/0304-4165(82)90197-0.
10
Defective binding of 3-methylcholanthrene to the Ah receptor within C3H/1OT1/2 clone 8 mouse fibroblasts in culture.培养的C3H/1OT1/2克隆8小鼠成纤维细胞内3-甲基胆蒽与芳烃受体的结合缺陷。
Eur J Biochem. 1983 May 2;132(2):219-27. doi: 10.1111/j.1432-1033.1983.tb07351.x.

引用本文的文献

1
Cinnabarinic acid protects against metabolic dysfunction-associated steatohepatitis by activating aryl hydrocarbon receptor-dependent AMPK signaling.朱红酸通过激活芳烃受体依赖性AMPK信号通路预防代谢功能障碍相关脂肪性肝炎。
Am J Physiol Gastrointest Liver Physiol. 2025 Apr 1;328(4):G433-G447. doi: 10.1152/ajpgi.00337.2024. Epub 2025 Mar 10.
2
Natural antagonistic flavones for AhR inhibit indoxyl sulfate-induced inflammatory gene expression and renal pathological damages .AhR的天然拮抗黄酮可抑制硫酸吲哚酚诱导的炎症基因表达和肾脏病理损伤。
Food Nutr Res. 2024 Jul 31;68. doi: 10.29219/fnr.v68.10032. eCollection 2024.
3
Role of Hepatic Aryl Hydrocarbon Receptor in Non-Alcoholic Fatty Liver Disease.
肝脏芳烃受体在非酒精性脂肪性肝病中的作用
Receptors (Basel). 2023 Mar;2(1):1-15. doi: 10.3390/receptors2010001. Epub 2023 Jan 4.
4
From Nucleus to Organs: Insights of Aryl Hydrocarbon Receptor Molecular Mechanisms.从核到器官:芳香烃受体分子机制的见解。
Int J Mol Sci. 2022 Nov 29;23(23):14919. doi: 10.3390/ijms232314919.
5
Polycyclic Aromatic Hydrocarbon Levels in Wistar Rats Exposed to Ambient Air of Port Harcourt, Nigeria: An Indicator for Tissue Toxicity.尼日利亚哈科特港环境空气中暴露的Wistar大鼠体内多环芳烃水平:组织毒性指标
Int J Environ Res Public Health. 2021 May 26;18(11):5699. doi: 10.3390/ijerph18115699.
6
Indol-3-Carbinol and Quercetin Ameliorate Chronic DSS-Induced Colitis in C57BL/6 Mice by AhR-Mediated Anti-Inflammatory Mechanisms.吲哚-3-甲醇和槲皮素通过 AhR 介导的抗炎机制改善 C57BL/6 小鼠慢性 DSS 诱导的结肠炎。
Int J Environ Res Public Health. 2021 Feb 25;18(5):2262. doi: 10.3390/ijerph18052262.
7
Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in Zebrafish (Danio rerio).AHR1b 在斑马鱼(Danio rerio)中对核因子红细胞 2 相关因子(nrfs)的发育调控。
Toxicol Sci. 2019 Feb 1;167(2):536-545. doi: 10.1093/toxsci/kfy257.
8
Ah Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-Motifs.芳烃受体途径的复杂性;通过多种蛋白质伴侣和DNA基序进行信号传导。
Toxicol Res (Camb). 2015 Sep 1;4(5):1143-1158. doi: 10.1039/c4tx00236a. Epub 2015 Mar 17.
9
Naturally occurring marine brominated indoles are aryl hydrocarbon receptor ligands/agonists.天然存在的海洋溴代吲哚是芳烃受体配体/激动剂。
Chem Res Toxicol. 2015 Jun 15;28(6):1176-85. doi: 10.1021/acs.chemrestox.5b00003. Epub 2015 Jun 2.
10
Lack of ligand-selective binding of the aryl hydrocarbon receptor to putative DNA binding sites regulating expression of Bax and paraoxonase 1 genes.芳烃受体缺乏配体选择性结合,无法调节 Bax 和对氧磷酶 1 基因表达的假定 DNA 结合位点。
Arch Biochem Biophys. 2014 Jan 1;541:13-20. doi: 10.1016/j.abb.2013.10.021. Epub 2013 Nov 4.