Sachs B A, Siegel E, Horwitt B N, Siegel E
Br Med J. 1972 Jan 8;1(5792):79-81. doi: 10.1136/bmj.1.5792.79.
The iodine content of bread consumed in the Bronx, New York, was found to be significantly lower than that of bread consumed in Columbia, Missouri. This difference in dietary intake of iodine could account for the lowered range of normal values for 24-hour (131)I uptake tests in Columbia, and the persistence of the same normal range for this test over the past 28 years in the Bronx. A population with high iodine intake requires higher doses of radioactive iodine in the diagnosis and treatment of thyroid disease. Questions are raised regarding the relationship of high iodine intake to the risk of developing thyrotoxicosis.
据发现,纽约布朗克斯区食用面包的碘含量显著低于密苏里州哥伦比亚市食用面包的碘含量。碘摄入量的这种差异可以解释哥伦比亚市24小时(131)I摄取试验正常数值范围较低的原因,以及在过去28年里布朗克斯区该试验正常范围一直保持不变的情况。碘摄入量高的人群在甲状腺疾病的诊断和治疗中需要更高剂量的放射性碘。由此引发了关于高碘摄入量与发生甲状腺毒症风险之间关系的疑问。