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抑制正常甲状腺摄取碘-131所需的最低碘剂量。

Minimal dosage of iodide required to suppress uptake of iodine-131 by normal thyroid.

作者信息

SAXENA K M, CHAPMAN E M, PRYLES C V

出版信息

Science. 1962 Oct 19;138(3538):430-1. doi: 10.1126/science.138.3538.430.

DOI:10.1126/science.138.3538.430
PMID:13986973
Abstract

Sodium iodide was given in increasing doses to mentally defective children with normal thyroid function. Maximal suppression of iodine-131 uptake was achieved with 1500 to 2000 micrograms of iodide per square meter of body surface per day, but quickly rebounded when iodide was discontinued. This minimal effective dose is important if countermeasures against fallout are employed.

摘要

给甲状腺功能正常的智力缺陷儿童服用递增剂量的碘化钠。每天每平方米体表面积给予1500至2000微克碘化物时,可实现对碘-131摄取的最大抑制,但停用碘化物后其摄取量会迅速反弹。如果采取应对放射性沉降物的措施,这个最小有效剂量很重要。

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Minimal dosage of iodide required to suppress uptake of iodine-131 by normal thyroid.抑制正常甲状腺摄取碘-131所需的最低碘剂量。
Science. 1962 Oct 19;138(3538):430-1. doi: 10.1126/science.138.3538.430.
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Plasma inorganic iodide, a chemical regulator of normal thyroid function.血浆无机碘,正常甲状腺功能的一种化学调节物质。
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Special methods for the determination of thyroid uptake of iodine. The author's reply.
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The hypothalamic-pituitary-thyroid axis in infants and children: protection from radioiodines.婴幼儿下丘脑-垂体-甲状腺轴:免受放射性碘的影响。
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3
Clinical dilemmas arising from the increased intake of iodine in the Spanish population and the recommendation for systematic prescription of potassium iodide in pregnant and lactating women (Consensus of the TDY Working Group of SEEN).
西班牙人群碘摄入量增加引发的临床困境以及对孕妇和哺乳期妇女系统性开具碘化钾的建议(SEEN的TDY工作组共识)
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[DIGLYCOLIC ACID BIS(3-CARBOXY-2,4,6-TRIIODOANILIDE) (IOGLYCAMID), A NEW CONTRAST MEDIUM FOR INTRAVENOUS CHOLANGIOGRAPHY].[二乙醇酸双(3-羧基-2,4,6-三碘苯胺)(碘甘酰胺),一种用于静脉胆管造影的新型造影剂]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1964 Jul 28;247:493-508. doi: 10.1007/BF00329897.
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IMPLICATIONS OF IODINE 131 IN FALLOUT.碘131在沉降物中的影响。
Public Health Rep (1896). 1964 Jan;79(1):25-31.
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Environ Health Perspect. 2000 Aug;108(8):679-84. doi: 10.1289/ehp.00108679.
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Bread iodine content and thyroid radioiodine uptake: a tale of two cities.面包碘含量与甲状腺放射性碘摄取:双城故事
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