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一种使用非放射性铬测量红细胞存活期的改进方法。

An improved method for the measurement of red cell survival using non-radioactive chromium.

作者信息

Drysdale H C, Emerson P M, Holmes A

出版信息

J Clin Pathol. 1979 Jul;32(7):655-9. doi: 10.1136/jcp.32.7.655.

DOI:10.1136/jcp.32.7.655
PMID:500836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1145771/
Abstract

An improved technique for the measurement of red cell survival is described in which non-radioactive 50Cr is used in patients for whom radioactive labels are not advisable. The 50Cr was measured by neutron activation analysis using a high resolution germanium (lithium) diode gamma-ray spectrometer. In adult controls, the values obtained were in the range accepted as normal for the 51Cr method, and double labelling experiments showed close agreement. The application of this technique to the measurement of red cell survival in pregnant women suspected of having haemolytic anemia is described.

摘要

本文描述了一种改进的红细胞存活时间测量技术,该技术使用非放射性的50Cr,适用于不宜使用放射性标记物的患者。50Cr通过中子活化分析,使用高分辨率锗(锂)二极管γ射线光谱仪进行测量。在成年对照组中,所获得的值处于51Cr法公认的正常范围内,双标记实验显示两者结果高度一致。本文还描述了该技术在疑似溶血性贫血孕妇红细胞存活时间测量中的应用。

相似文献

1
An improved method for the measurement of red cell survival using non-radioactive chromium.一种使用非放射性铬测量红细胞存活期的改进方法。
J Clin Pathol. 1979 Jul;32(7):655-9. doi: 10.1136/jcp.32.7.655.
2
Red cell survival time in man measured by 50Cr and activation analysis.通过50Cr和活化分析测定人体红细胞存活时间。
Br Med J. 1968 Jun 8;2(5605):585-7. doi: 10.1136/bmj.2.5605.585.
3
Erythrocyte survival in children as studied by labeling with stable 50Cr.通过用稳定的50Cr标记研究儿童红细胞的存活情况。
Am J Dis Child. 1976 Nov;130(11):1228-30. doi: 10.1001/archpedi.1976.02120120062010.
4
Congenital hemolytic anemia with high-sodium, low-potassium red cells. Studies of three generations of a family with a new variant.伴有高钠低钾红细胞的先天性溶血性贫血。一个具有新变异型的家族三代人的研究。
N Engl J Med. 1969 Apr 24;280(17):909-16. doi: 10.1056/NEJM196904242801701.
5
[Blood volume measurement of newborn using stable isotope 50Cr].
Radioisotopes. 1985 Mar;34(3):144-50. doi: 10.3769/radioisotopes.34.3_144.
6
Radioisotope investigations in some hemolytic disorders of children.儿童某些溶血性疾病的放射性同位素研究
Med Interne. 1977 Jan-Mar;15(1):79-83.
7
[THE SIGNIFICANCE OF QUANTITATIVE HAPTOGLOBIN DETERMINATION IN THE DIAGNOSIS OF HEMOLYTIC DISEASES].[血清结合珠蛋白定量测定在溶血性疾病诊断中的意义]
Dtsch Med Wochenschr. 1964 Apr 17;89:785-9. doi: 10.1055/s-0028-1111087.
8
Pregnancy complicated by hereditary spherocytosis.妊娠合并遗传性球形红细胞增多症。
Obstet Gynecol. 1992 May;79(5 ( Pt 1)):735-8.
9
The use of Cr 51 in the assessment of the role of the spleen in red cell destruction.铬51在评估脾脏在红细胞破坏中作用的应用。
Nucl Med (Stuttg). 1963;2:Suppl 1:185-93.
10
Recent progress in research on red cell membrane disorders in Japan: pathogenesis of microspherocytosis in hereditary spherocytosis, sodium transport abnormalities in stomatocytosis, and homeo-adaptive compensatory mechanism for membrane fluidity in red cell membrane lipid abnormalities.
Nihon Ketsueki Gakkai Zasshi. 1983 Dec;46(7):1426-40.

本文引用的文献

1
Chronic toxicity studies. III. Chronic toxicity of cadmium and chromium in dogs.慢性毒性研究。III. 镉和铬对犬的慢性毒性
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2
Metabolism of Cr51 by animals as influenced by chemical state.动物对Cr51的代谢受化学状态的影响。
Proc Soc Exp Biol Med. 1953 Dec;84(3):610-5. doi: 10.3181/00379727-84-20729.
3
The use of radioactive chromium 51 as an erythrocyte tagging agent for the determination or red cell survival in vivo.使用放射性铬51作为红细胞标记剂来测定体内红细胞存活情况。
J Clin Invest. 1953 Dec;32(12):1260-76. doi: 10.1172/JCI102855.
4
Radioactive sodium chromate for the study of survival of red blood cells. I. The effect of radioactive sodium chromate on red cells.用于研究红细胞存活的放射性铬酸钠。I. 放射性铬酸钠对红细胞的影响。
J Lab Clin Med. 1953 Sep;42(3):358-67.
5
Stable chromium as a tracer for red cells, with assay by neutron activation analysis.稳定铬作为红细胞示踪剂,采用中子活化分析法进行测定。
Int J Appl Radiat Isot. 1969 Feb;20(2):103-8. doi: 10.1016/0020-708x(69)90146-x.
6
Red cell survival time in man measured by 50Cr and activation analysis.通过50Cr和活化分析测定人体红细胞存活时间。
Br Med J. 1968 Jun 8;2(5605):585-7. doi: 10.1136/bmj.2.5605.585.
7
Life-span and organ sequestration of the red cells in pyruvate kinase deficiency.
N Engl J Med. 1968 Jan 11;278(2):73-81. doi: 10.1056/NEJM196801112780203.
8
Determination of red cell survival by activation analysis.通过活化分析测定红细胞存活率。
Int J Nucl Med Biol. 1975 Jan;2(1):37-40. doi: 10.1016/0047-0740(75)90019-4.
9
Erythrocyte survival in children as studied by labeling with stable 50Cr.通过用稳定的50Cr标记研究儿童红细胞的存活情况。
Am J Dis Child. 1976 Nov;130(11):1228-30. doi: 10.1001/archpedi.1976.02120120062010.