Drysdale H C, Emerson P M, Holmes A
J Clin Pathol. 1979 Jul;32(7):655-9. doi: 10.1136/jcp.32.7.655.
An improved technique for the measurement of red cell survival is described in which non-radioactive 50Cr is used in patients for whom radioactive labels are not advisable. The 50Cr was measured by neutron activation analysis using a high resolution germanium (lithium) diode gamma-ray spectrometer. In adult controls, the values obtained were in the range accepted as normal for the 51Cr method, and double labelling experiments showed close agreement. The application of this technique to the measurement of red cell survival in pregnant women suspected of having haemolytic anemia is described.
本文描述了一种改进的红细胞存活时间测量技术,该技术使用非放射性的50Cr,适用于不宜使用放射性标记物的患者。50Cr通过中子活化分析,使用高分辨率锗(锂)二极管γ射线光谱仪进行测量。在成年对照组中,所获得的值处于51Cr法公认的正常范围内,双标记实验显示两者结果高度一致。本文还描述了该技术在疑似溶血性贫血孕妇红细胞存活时间测量中的应用。