Fellows K E, Khaw K T, Schuster S, Shwachman H
J Pediatr. 1979 Dec;95(6):959-63. doi: 10.1016/s0022-3476(79)80283-8.
Severe bronchial hemorrhage in 13 patients with cystic fibrosis was treated by catheter embolization of bronchial arteries. Indications were either excessive bleeding persisting for several days, or bleeding serious enough to interfere with pulmonary drainage and recurring over weeks or months. In follow-up ranging from one to 30 months, cessation of major bleeding was achieved in 12 of 13 patients (93%), although 5 of 13 patients (40%) did have recurrence of minor hemoptysis. No neurologic or other major complications were encountered. However, there are potential risks and this approach at present should be limited to patients with life-threatening bleeding and carried out only by experienced angiographers.
对13例囊性纤维化患者的严重支气管出血进行了支气管动脉导管栓塞治疗。适应症为持续数天的大量出血,或严重到足以干扰肺引流且在数周或数月内反复出现的出血。在1至30个月的随访中,13例患者中有12例(93%)实现了大出血停止,尽管13例患者中有5例(40%)确实有少量咯血复发。未遇到神经或其他重大并发症。然而,存在潜在风险,目前这种方法应仅限于有危及生命出血的患者,并且仅由经验丰富的血管造影师进行。