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通过反复支气管动脉栓塞和长期使用氨甲环酸治疗一名患有囊性纤维化儿童的复发性咯血。

Treatment of recurrent hemoptysis in a child with cystic fibrosis by repeated bronchial artery embolizations and long-term tranexamic acid.

作者信息

Wong L T, Lillquist Y P, Culham G, DeJong B P, Davidson A G

机构信息

Department of Paediatrics, University of British Columbia, Vancouver, Canada.

出版信息

Pediatr Pulmonol. 1996 Oct;22(4):275-9. doi: 10.1002/(SICI)1099-0496(199610)22:4<275::AID-PPUL8>3.0.CO;2-L.

DOI:10.1002/(SICI)1099-0496(199610)22:4<275::AID-PPUL8>3.0.CO;2-L
PMID:8905889
Abstract

The course of a 12-year-old girl with cystic fibrosis (CF) and with recurrent hemoptysis since age 8 years is described. Conservative measures failed to control her bleeding. Hemoptysis was only partially controlled by repeated bronchial arterial embolizations. However, the addition of tranexamic acid (TXA) resulted in complete cessation of bleeding. Attempts to withdraw TXA therapy resulted in recurrence of hemoptysis; this patient has, therefore, been continuously maintained on this therapy for the past 4 years. No side effects of long-term TXA treatment have been noted.

摘要

本文描述了一名12岁患有囊性纤维化(CF)的女孩的病程,她自8岁起就反复咯血。保守治疗措施未能控制她的出血。反复进行支气管动脉栓塞术只能部分控制咯血。然而,加用氨甲环酸(TXA)后出血完全停止。尝试停用TXA治疗导致咯血复发;因此,该患者在过去4年中一直持续接受这种治疗。未发现长期TXA治疗的副作用。

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Treatment of recurrent hemoptysis in a child with cystic fibrosis by repeated bronchial artery embolizations and long-term tranexamic acid.通过反复支气管动脉栓塞和长期使用氨甲环酸治疗一名患有囊性纤维化儿童的复发性咯血。
Pediatr Pulmonol. 1996 Oct;22(4):275-9. doi: 10.1002/(SICI)1099-0496(199610)22:4<275::AID-PPUL8>3.0.CO;2-L.
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