Desai H G, Zaveri M P, Antia F P
Postgrad Med J. 1972 Feb;48(556):87-90. doi: 10.1136/pgmj.48.556.87.
Dose-response curves were obtained from forty male control subjects and forty male patients with duodenal ulcer from India on the subcutaneous histamine test. The body weight and maximal acid output (MAO) showed a positive correlation just significant at the 5% level in control subjects (=0·05) but not in patients with duodenal ulcer. The values of MAO on dose-response curves are comparable in control subjects but are appreciably lower in patients with duodenal ulcer from India compared with those from Britain and North America. However, the values expressed as μEq/kg body weight are considerably higher in both groups of subjects from India compared with those from western populations.
对40名印度男性对照受试者和40名患有十二指肠溃疡的印度男性患者进行皮下组胺试验，获得了剂量反应曲线。在对照受试者中，体重与最大胃酸分泌量（MAO）呈正相关，在5%水平上具有显著性（=0·05），但在十二指肠溃疡患者中无此相关性。对照受试者剂量反应曲线上的MAO值具有可比性，但与来自英国和北美的十二指肠溃疡患者相比，印度十二指肠溃疡患者的MAO值明显更低。然而，以每千克体重微当量表示的值在两组印度受试者中均明显高于西方人群。
