Seaton A
Thorax. 1972 Jan;27(1):75-9. doi: 10.1136/thx.27.1.75.
Pulmonary capillary blood volume (V) was determined in 30 young women, 14 of whom were taking oral contraceptives. Duplicate estimates of V in the 16 women not taking contraceptives showed a significant increase in the second half of the menstrual cycle. Formulae for prediction of V in women were derived for the first and second halves of the cycle. V was shown to be of the same order in women taking contraceptives containing oestrogen and progestogen as in those in the premenstrual phase of the cycle. Possible causes of these findings and their relevance to the diagnosis of pulmonary thromboembolic disease are discussed.
对30名年轻女性测定了肺毛细血管血容量(V),其中14名正在服用口服避孕药。对16名未服用避孕药的女性进行的V值重复测量显示,月经周期后半期V值显著增加。推导了女性月经周期前半期和后半期V值的预测公式。结果表明,服用含雌激素和孕激素避孕药的女性的V值与月经周期经前期女性的V值处于同一水平。讨论了这些发现的可能原因及其与肺血栓栓塞性疾病诊断的相关性。