口服避孕药与可溶性纤维蛋白形成增加
Oral contraceptives and increased formation of soluble fibrin.
作者信息
Pilgeram L O, Ellison J, Von dem Bussche G
出版信息
Br Med J. 1974 Aug 31;3(5930):556-8. doi: 10.1136/bmj.3.5930.556.
Abstract
Soluble fibrin was measured weekly for two months in 12 normal women and in 12 women on combined oestrogen-progestogen therapy (Ortho-Novin, Norinyl, Enavid, Ovral, Ovulen, Demulen). Plasma soluble fibrin concentration in women on oral contraceptives showed an increase of 97.2% (P <0.001) above that of normal women. In three cases, where each woman on the oral contraceptive served as her own control, stopping medication led to a return to normal of the plasma content of soluble fibrin.
摘要
在12名正常女性和12名接受雌激素 - 孕激素联合治疗（炔诺酮炔雌醇片、复方炔诺酮片、炔雌醇甲醚片、复方炔诺孕酮片、复方炔孕酮片、复方甲地孕酮片）的女性中，连续两个月每周测量可溶性纤维蛋白。口服避孕药女性的血浆可溶性纤维蛋白浓度比正常女性高出97.2%（P<0.001）。在3例口服避孕药的女性中，每例女性以自身作为对照，停药后血浆可溶性纤维蛋白含量恢复正常。
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Oral contraceptives and increased formation of soluble fibrin.口服避孕药与可溶性纤维蛋白形成增加
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Thromb Diath Haemorrh. 1964 Apr 15;11:94-8.
2
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J Clin Pathol. 1964 May;17(3):307-9. doi: 10.1136/jcp.17.3.307.
3
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Br Med J. 1964 Apr 4;1(5387):883-4. doi: 10.1136/bmj.1.5387.883.
4
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Am J Clin Pathol. 1961 Sep;36:212-9. doi: 10.1093/ajcp/36.3.212.
5
Relation of plasma fibrinogen concentration changes to human arteriosclerosis.血浆纤维蛋白原浓度变化与人类动脉粥样硬化的关系。
J Appl Physiol. 1961 Jul;16:660-4. doi: 10.1152/jappl.1961.16.4.660.
6
Thromboembolic complications during and after cortisone and ACTH therapy.可的松和促肾上腺皮质激素治疗期间及之后的血栓栓塞并发症。
Postgrad Med J. 1956 Sep;32(371):444-6. doi: 10.1136/pgmj.32.371.444.
7
Antagonistic effect of A.C.T.H. and cortisone on the anticoagulant activity of ethyl biscoumacetate.促肾上腺皮质激素（ACTH）和可的松对双香豆乙酯抗凝活性的拮抗作用。
Br Med J. 1954 Oct 2;2(4891):790-2. doi: 10.1136/bmj.2.4891.790.
8
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Schweiz Med Wochenschr. 1954 Jul 17;84(29):835-8.
9
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J Clin Invest. 1971 Nov;50(11):2235-41. doi: 10.1172/JCI106720.
10
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