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一种小肠活检标本的定量方法。

A method for the quantitation of small intestinal biopsy specimens.

作者信息

Dunnill M S, Whitehead R

出版信息

J Clin Pathol. 1972 Mar;25(3):243-6. doi: 10.1136/jcp.25.3.243.

DOI:10.1136/jcp.25.3.243
PMID:5018715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC477271/
Abstract

A simple method is described for the quantitative examination of small intestinal mucosal biopsies involving the determination of an index related to the surface-to-volume ratio of the mucosa. The method is of value in distinguishing minor degrees of villous abnormality and will prove useful in comparing serial changes in a given patient. It will also allow comparisons to be made between biopsies taken in different medical centres.

摘要

本文描述了一种用于小肠黏膜活检定量检查的简单方法,该方法涉及测定一个与黏膜表面积与体积比相关的指标。该方法对于区分轻度绒毛异常具有重要价值,并且在比较特定患者的系列变化时将证明是有用的。它还将允许对不同医疗中心采集的活检样本进行比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e1a/477271/8af56cd50d8f/jclinpath00101-0060-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e1a/477271/8af56cd50d8f/jclinpath00101-0060-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e1a/477271/8af56cd50d8f/jclinpath00101-0060-a.jpg

相似文献

1
A method for the quantitation of small intestinal biopsy specimens.一种小肠活检标本的定量方法。
J Clin Pathol. 1972 Mar;25(3):243-6. doi: 10.1136/jcp.25.3.243.
2
[Anatomo-functional correlates in villous atrophy in the adult. Results provided by staggered biopsies of the small intestine].[成人绒毛萎缩的解剖功能相关性。小肠分期活检的结果]
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[Mucosal lesions of the small intestine in diet-induced malabsorption in infancy].[婴儿饮食性吸收不良时小肠的黏膜病变]
Kinderarztl Prax. 1973 Feb;41(2):51-63.
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[Biopsy examinations of small intestinal mucosa in malabsorption syndrome of childhood].[儿童吸收不良综合征中小肠黏膜的活检检查]
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Role of the pathologist in the differential diagnosis of malabsorption.病理学家在吸收不良鉴别诊断中的作用。
Acta Gastroenterol Belg. 2006 Jan-Mar;69(1):49-51.
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Quantitation of the histological changes found in small intestinal biopsy specimens from children with suspected coeliac disease.对疑似乳糜泻儿童小肠活检标本中发现的组织学变化进行定量分析。
Gut. 1974 Jan;15(1):9-18. doi: 10.1136/gut.15.1.9.
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[Mitotic activity of small intestine mucosa in children with malabsorption syndromes].[吸收不良综合征患儿小肠黏膜的有丝分裂活性]
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The quantitative assessment of mucosa in canine small intestinal malabsorption.犬小肠吸收不良中黏膜的定量评估
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[Assessment of the correlations of certain clinical and laboratory data with the morphological pattern of small intestine mucosa in the malabsorption syndrome in children].[儿童吸收不良综合征中某些临床和实验室数据与小肠黏膜形态学模式的相关性评估]
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2
Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease.上皮来源的白细胞介素15调节乳糜泻中上皮内淋巴细胞Th1细胞因子的产生、细胞毒性和存活。
Gut. 2006 Apr;55(4):469-77. doi: 10.1136/gut.2005.068684. Epub 2005 Aug 16.
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Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease?

本文引用的文献

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A Method for Estimating Volume-Surface Ratios.一种估计体积-表面积比的方法。
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Histopathologic studies in steatorrhea.脂肪痢的组织病理学研究。
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绒毛尖端的上皮内淋巴细胞:它们是否预示着潜在的乳糜泻?
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Mechanisms of villous atrophy in autoimmune enteropathy and coeliac disease.自身免疫性肠病和乳糜泻中绒毛萎缩的机制。
Clin Exp Immunol. 2002 Apr;128(1):88-93. doi: 10.1046/j.1365-2249.2002.01795.x.
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Activation of caspases in intestinal villus epithelial cells of normal and nematode infected rats.正常大鼠和感染线虫大鼠肠绒毛上皮细胞中半胱天冬酶的激活。
Gut. 2002 Jan;50(1):71-7. doi: 10.1136/gut.50.1.71.
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Intraepithelial and lamina propria lymphocytes show distinct patterns of apoptosis whereas both populations are active in Fas based cytotoxicity in coeliac disease.上皮内淋巴细胞和固有层淋巴细胞表现出不同的凋亡模式,而在乳糜泻中这两种细胞群在基于Fas的细胞毒性方面均很活跃。
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HIV enteropathy: comparative morphometry of the jejunal mucosa of HIV infected patients resident in the United Kingdom and Uganda.HIV 肠道病:居住在英国和乌干达的 HIV 感染患者空肠黏膜的比较形态计量学
Gut. 1998 Sep;43(3):350-5. doi: 10.1136/gut.43.3.350.
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Increased production of tumour necrosis factor-alpha interleukin-1 beta, and interleukin-6 by morphologically normal intestinal biopsies from patients with Crohn's disease.克罗恩病患者形态学正常的肠道活检组织中肿瘤坏死因子-α、白细胞介素-1β和白细胞介素-6的产生增加。
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Analysis of crypt cell proliferation in coeliac disease using MI-B1 antibody shows an increase in growth fraction.使用MI-B1抗体对乳糜泻隐窝细胞增殖进行分析显示生长分数增加。
Gut. 1995 Jan;36(1):22-7. doi: 10.1136/gut.36.1.22.
10
Measurement in jejunal biopsies by computer-aided microscopy.通过计算机辅助显微镜对空肠活检组织进行测量。
J Clin Pathol. 1980 Mar;33(3):254-61. doi: 10.1136/jcp.33.3.254.
Gastroenterology. 1960 Apr;38:517-32.
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SMALL-BOWEL DISEASE IN ROSACEA.
Lancet. 1965 Jul 10;1(7402):47-50. doi: 10.1016/s0140-6736(65)90128-5.
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MEASUREMENTS OF SMALL INTESTINAL MUCOSA OBTAINED BY PERORAL BIOPSY.经口活检获取的小肠黏膜测量
Am J Med. 1965 Jan;38:42-53. doi: 10.1016/0002-9343(65)90158-0.
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Principles and methods for the morphometric study of the lung and other organs.肺及其他器官形态测量研究的原理与方法。
Lab Invest. 1963 Feb;12:131-55.
7
The histopathologic changes of sprue and their significance.口炎性腹泻的组织病理学变化及其意义。
Am J Clin Pathol. 1960 Aug;34:108-17. doi: 10.1093/ajcp/34.2.108.
8
A study of proximal and distal intestinal structure and absorptive function in idiopathic steatorrhoea.特发性脂肪泻患者近端及远端肠道结构与吸收功能的研究
Q J Med. 1967 Jul;36(143):425-44.
9
Peroral biopsy of the small intestine. A review of its diagnostic usefulness.小肠经口活检。其诊断效用综述。
Gastroenterology. 1965 Dec;49(6):676-97.