Ichioka T, Miyao M
Jpn J Antibiot. 1979 Sep;32(9):901-4.
In order to evaluate efficacy and safety, cefamandole, a new cephalosporin, was given intravenously to 12 children with respiratory tract infections (11 cases) and urinary tract infection (1 case), who ranged in age from 2 months to 5 years old. Cefamandole sodium was administered 74 approximately 112 mg/kg/day in three or four equally divided doses by one-shot injection. The overall efficacy rate was 83.3% in 12 cases, i.e., good in 8, fairly good in 2, and poor in 2 cases. No adverse reaction was noted on any of our 12 cases.
为评估新型头孢菌素头孢孟多的疗效和安全性,对12例2个月至5岁的呼吸道感染患儿(11例)和尿路感染患儿(1例)静脉注射该药。头孢孟多钠按每日约74至112mg/kg,分三或四次等量注射给药。12例患儿的总有效率为83.3%,即8例显效,2例有效,2例无效。12例患儿均未出现不良反应。