通过放射免疫分析法在大鼠可移植肝癌中检测到甲胎蛋白。
alpha-Fetoprotein detected in rat transplantable hepatomas by radioimmunoassay.
作者信息
Watabe H, Nishi S, Hirai H
出版信息
Gan. 1975 Apr;66(2):197-8.
PMID:50249
Abstract
Production of rat alpha-fetoprotein by transplantable ascites hepatoma was studied by radioimmunoassay method. alpha-Fetoprotein was detected in sera from rats bearing 22 out of 50 ascites hepatoma cell lines that were previously negative for the presence of alpha-fetoprotein by the Ouchterlony test. alpha-Fetoprotein was also detected with high prevalency in Morris hepatomas and sublines of Yoshida sarcoma by this assay system.
摘要
采用放射免疫分析法研究了可移植性腹水肝癌大鼠甲胎蛋白的产生情况。通过免疫双扩散试验，先前50种腹水肝癌细胞系中有22种甲胎蛋白呈阴性，但在携带这些细胞系的大鼠血清中检测到了甲胎蛋白。利用该检测系统，在莫里斯肝癌和吉田肉瘤亚系中也检测到了高阳性率的甲胎蛋白。
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