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人成纤维细胞间期核中同源染色体(9号染色体和YY染色体)的非随机定位(作者译)

[Non-random position of homologous chromosomes (no. 9 and YY) in interphase nuclei of human fibroblasts (author's transl)].

作者信息

Spaeter M

出版信息

Humangenetik. 1975;27(2):111-8.

PMID:50271
Abstract

The position of chromosomes No. 9 and of the Y chromosomes in interphase nuclei was observed by means of the Giemsa-11 staining and the quinacrine mustard fluorescence staining respectively. 3 fibroblast cultures from normal female persons and 1 culture from a person with the karyotype 47/XYY were used. The distance between the two homologous chromosomes was compared with the theoretical expected distance between two points which are randomly positioned in a circular area. The distance between the chromosomes No. 9 as well as between the two Y chromosomes is significantly smaller than expected with a random position. This tendency for a somatic association is stronger in the case of the two Y chromosomes than in the two chromosomes No. 9.

摘要

分别通过吉姆萨 - 11染色和喹吖因芥子荧光染色观察了9号染色体和Y染色体在间期核中的位置。使用了来自正常女性的3种成纤维细胞培养物和来自核型为47/XYY个体的1种培养物。将两条同源染色体之间的距离与在圆形区域中随机定位的两点之间的理论预期距离进行了比较。9号染色体之间以及两条Y染色体之间的距离明显小于随机定位时的预期距离。两条Y染色体的这种体细胞关联倾向比两条9号染色体更强。

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