Klasen M, Schmid M
Hum Genet. 1981;58(2):156-61. doi: 10.1007/BF00278701.
The fluorescence of Y-bodies and brightly fluorescing autosomal heterochromatin in quinacrine mustard stained interphase nuclei treated with distamycin A is more brilliant than in nuclei stained only with quinacrine and mustard. In the present study examinations with the aid of this method in several probands and different tissues are described. The effect of distamycin A is demonstrated to depend on its dose and the time of exposure to it. An exceptionally high frequency of YY sperm nuclei, previously also described by other studies, is confirmed in the present work. A hypothesis explaining the effect of distamycin A in interphase nuclei is discussed.
在用放线菌素 A 处理的喹吖因氮芥染色的间期核中，Y 小体和常染色体异染色质发出的明亮荧光比仅用喹吖因和氮芥染色的核更亮。在本研究中，描述了借助该方法对几个先证者和不同组织进行的检查。已证明放线菌素 A 的作用取决于其剂量和暴露于它的时间。本研究证实了此前其他研究也描述过的 YY 精子核的异常高频率。讨论了解释放线菌素 A 在间期核中作用的一个假说。
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