Flammang D, Sebastien P, Bouvrain Y
Ann Anesthesiol Fr. 1975 Dec;16(9):669-72.
The object of this study is to examine the properties of dopamine at the hemodynamic and renal level in 16 patients with decompensated chronic cardiopathies or very serious cardiogenic shock due to myocardial infarction. The results show an increase in the cardiac index in 75 p. 100 of the cases with a favourable diminution of the arterio-venous difference in O2 and of the pulmonary arterial resistances. The most noticeable and the most constant effect is the recovery and increase of the diuresis. Positive chronotropic and bathmotropic effects were observed which necessitated the limitation of prescription of dopamine in those subjects showing signs of disturbances in ventricular excitability.
本研究的目的是检测16例失代偿性慢性心脏病患者或因心肌梗死导致的非常严重的心源性休克患者体内多巴胺在血流动力学和肾脏方面的特性。结果显示,75%的病例心脏指数增加,同时氧动静脉差和肺动脉阻力均出现了有利的降低。最显著且最持续的作用是尿量的恢复和增加。观察到了正性变时和变力作用,因此对于那些出现心室兴奋性紊乱迹象的患者,有必要限制多巴胺的处方用量。