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[内科急症中的儿茶酚胺]

[Catecholamines in internal medicine emergencies].

作者信息

Brandt D, Pristautz H, Klein W

出版信息

Wien Med Wochenschr. 1984 Jul 31;134(13-14):324-7.

PMID:6495745
Abstract

The most important indications for the application of the catecholamines dopamine and dobutamine in the internal intensive medical care are acute disturbances of the peripheral vascular regulation and acute heart failure. Differential therapeutic considerations are due to the different actions of both pharmaceutics. Disturbances in peripheral circulation and in renal function are of great importance in case of the septic shock. Dopamine is highly advisable for its vascular and renal efficacy. Whereas the application of dobutamine or a therapy combining the application of dobutamine and dopamine has to be preferred in case of a cardiogenic shock. A retrospective examination has shown that the mortality of patients with a cardiogenic shock after an acute myocardial infarction could be lowered by a therapy of the current catecholamines dobutamine and dopamine.

摘要

在内部重症监护中应用儿茶酚胺类药物多巴胺和多巴酚丁胺的最重要指征是外周血管调节急性紊乱和急性心力衰竭。由于这两种药物的作用不同,存在不同的治疗考量。在脓毒性休克时,外周循环和肾功能紊乱非常重要。多巴胺因其血管和肾脏功效而非常适用。而在心源性休克时,多巴酚丁胺的应用或多巴酚丁胺与多巴胺联合应用的疗法更值得推荐。一项回顾性研究表明,急性心肌梗死后发生心源性休克的患者,通过应用当前的儿茶酚胺类药物多巴酚丁胺和多巴胺进行治疗,死亡率可降低。

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