Bennett R C, Hughes E S
Br Med J. 1972 May 27;2(5812):494-6. doi: 10.1136/bmj.2.5812.494.
A survey of 458 patients treated for ulcerative colitis either medically or surgically by colectomy and the establishment of an ileostomy has provided further evidence that in Australia at least there is a significant association between ulcerative colitis and urinary calculi. The actual risk to the unoperated patient is not particularly high but is in the vicinity of 4%. The survey further confirms that the risk continues after colectomy and ileostomy, when the overall incidence of stones is roughly doubled. Finally, suggestive though admittedly somewhat inconclusive evidence supports the proposition that uric acid stones are more common in this group of patients.
一项对458例接受过溃疡性结肠炎治疗的患者的调查提供了进一步证据,这些患者有的接受了药物治疗,有的接受了结肠切除术及回肠造口术的外科治疗。该调查表明,至少在澳大利亚,溃疡性结肠炎与尿路结石之间存在显著关联。未接受手术治疗的患者实际患病风险并非特别高,但约为4%。该调查进一步证实,结肠切除术后及回肠造口术后风险依然存在,此时结石的总体发病率大致翻倍。最后,尽管证据有些不确定,但具有启发性的证据支持了这一观点,即尿酸结石在这组患者中更为常见。