Grolleau D, Kienlen J, Bessou D, du Cailar J
Ann Anesthesiol Fr. 1975 Dec;16(9):691-9.
Nineteen patients presenting cardiovascular distress were treated with dopamine. For seventeen of these, the accident occurred immediately after cardiac surgery. Dosages varied from 1 to 15 mug/kg/min and the duration of treatment from 10 minutes to three days. The efficacy of the treatment was judged according to the clinical and hemodynamic improvement of the cardio-circulatory function and the increase in urinary output. There were 15 favourable results. The positive effects of the dopamine seem to be limited in certain patients by the appearance of a cyanosis testifying to a rise in vascular resistances which increases the left auricular pressure and limits the inotropic effect. In these cases, isoproterenol or a combination of both isoproterenol and dopamine gives better results.
19例出现心血管窘迫的患者接受了多巴胺治疗。其中17例在心脏手术后立即发生意外。剂量从1至15微克/千克/分钟不等，治疗持续时间从10分钟至3天。根据心脏循环功能的临床和血流动力学改善情况以及尿量增加来判断治疗效果。有15例取得了良好效果。在某些患者中，多巴胺的积极作用似乎受到出现发绀的限制，这表明血管阻力增加，进而增加左心房压力并限制了正性肌力作用。在这些情况下，异丙肾上腺素或异丙肾上腺素与多巴胺联合使用效果更佳。
