底物类似物溴丙酮酸作为2-酮-3-脱氧-6-磷酸葡萄糖醛酸醛缩酶的底物和烷基化剂。动力学和立体化学研究。 - Suppr

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The substrate analog, bromopyruvate, as both a substrate and alkylating agent for 2-keto-3-deoxy-6-phosphogluconic aldolase. Kinetic and stereochemical studies.

作者信息

Meloche H P, Luczak M A, Wurster J M

出版信息

J Biol Chem. 1972 Jul 10;247(13):4186-91.

PMID:5035689

Abstract

摘要

相似文献

The substrate analog, bromopyruvate, as both a substrate and alkylating agent for 2-keto-3-deoxy-6-phosphogluconic aldolase. Kinetic and stereochemical studies.底物类似物溴丙酮酸作为2-酮-3-脱氧-6-磷酸葡萄糖醛酸醛缩酶的底物和烷基化剂。动力学和立体化学研究。

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The substrate analog, bromopyruvate, as a bridging agent for the active site of 2-keto-3-deoxy-6-phosphogluconic aldolase. Chemical evidence for a carboxylate adjacent to the Schiff's base-forming lysine.

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The mechanism of 2-keto-3-deoxy-6-phosphogluconic aldolase. II. Studies of the partial reactions with substrate analogues.2-酮-3-脱氧-6-磷酸葡糖醛缩酶的作用机制。II. 与底物类似物的部分反应研究。

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