Sommer F G, Laglia A, Goldberg R T
Radiology. 1979 Dec;133(3 Pt 1):790-1. doi: 10.1148/133.3.790.
Leg venography with either 50% sodium diatrizoate or 60% meglumine diatrizoate was performed on 31 patients suspected of having deep venous thrombophlebitis. Four of 14 patients receiving meglumine diatrizoate experienced pain during venography, as compared to 14 of 17 patients receiving sodium diatrizoate (p less than 0.004). A second study showed no statistically significant difference in the incidence of pain between two groups of patients receiving either Renografin-45 (6% sodium diatrizoate, 39% meglumine diatrizoate) or Renografin-M-45 (45% meglumine diatrizoate).
对31名疑似患有深部静脉血栓性静脉炎的患者进行了使用50%泛影葡胺或60%葡甲胺泛影葡胺的腿部静脉造影。接受葡甲胺泛影葡胺的14名患者中有4名在静脉造影期间出现疼痛，而接受泛影葡胺的17名患者中有14名出现疼痛（p小于0.004）。第二项研究表明，接受雷纳瑞芬-45（6%泛影葡胺，39%葡甲胺泛影葡胺）或雷纳瑞芬-M-45（45%葡甲胺泛影葡胺）的两组患者在疼痛发生率上无统计学显著差异。
