Curative potencies against -amanitin poisoning by cytochrome c.
作者信息
Floersheim G L
出版信息
Science. 1972 Sep 1;177(4051):808-9. doi: 10.1126/science.177.4051.808.
PMID:5052736
Abstract
The fatalities occurring after ingestion of the poisonous mushroom Amanita phalloides are thought to be due to alpha-amanitin. Cytochrome c provided antidotal effects against a lethal dose of this toxin in mice. Significant survival was obtained even when the treatment was withheld for 8 hours. The enzyme was superior to a previously explored therapeutic regimen consisting of penicillin and its combination with chloramphenicol and sulfamethoxazole.
摘要
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