Hassell T A, Renwick S, Stuart K L
Br Med J. 1972 Aug 12;3(5823):387-9. doi: 10.1136/bmj.3.5823.387.
The objectives of this study were to improve our methods of secondary prophylaxis of rheumatic fever and rheumatic heart disease in Barbados, to estimate the overall prevalence of these diseases and the relative load imposed by them on available health services, and to measure the yield, feasibility, and effectiveness of mass programmes for the detection and prophylactic management of rheumatic heart disease in schoolchildren.Improved methods of surveillance and follow-up resulted in 97% adherence to therapy by patients on prophylactic penicillin. Thirty-four children, 27 with a first attack, were admitted with acute rheumatic fever, representing a 7% occupancy of children's medical beds during the 12-month period of the study. Out of a possible 3,942 schoolchildren aged 5-11 years, 3,882 (98%) were screened for rheumatic heart disease. Four cases (about 1 per 1,000) were discovered.
本研究的目的是改进我们在巴巴多斯对风湿热和风湿性心脏病进行二级预防的方法,估计这些疾病的总体患病率以及它们对现有卫生服务造成的相对负担,并衡量针对学龄儿童风湿性心脏病检测和预防性管理的大规模项目的产出、可行性和有效性。改进的监测和随访方法使接受预防性青霉素治疗的患者治疗依从率达到97%。34名儿童因急性风湿热入院,其中27名是首次发作,在研究的12个月期间,占儿童病床使用率的7%。在3942名5至11岁的学龄儿童中,3882名(98%)接受了风湿性心脏病筛查。发现了4例(约每1000人中有1例)。