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约翰内斯堡索韦托黑人学童风湿性心脏病的流行病学

Epidemiology of rheumatic heart disease in black shcoolchildren of Soweto, Johannesburg.

作者信息

McLaren M J, Hawkins D M, Koornhof H J, Bloom K R, Bramwell-Jones D M, Cohen E, Gale G E, Kanarek K, Lachman A S, Lakier J B, Pocock W A, Barlow J B

出版信息

Br Med J. 1975 Aug 23;3(5981):474-8. doi: 10.1136/bmj.3.5981.474.

Abstract

A survey to determine the prevalence of rheumatic heart disease (R.H.D.) in Black children was conducted in the creeches and primary schools of the South Western Townships of Johannesburg (Soweto). A total of 12 050 Black children were examined by 10 cardiologists in May to October 1972. The overal prevalence rate of R.H.D. was 6.9 per 1000, with a peak rate of 19.2 per 1000 in children of the seventh school grade. The maximal age incidence was 15-18 years and there was a female preponderance of 1 6:1. A rise in prevalence occurred with increasing family size. Most children (92%) were asymptomatic, and in 82.5% R.H.D. was diagnosed for the first time during the school survey. The commonest valve lesion was mitral regurgitation, which was present in 93% and occurred as an isolated lesion in 47.5%. Lancefield's group A beta-haemolytic streptococcus was isolated from the throats of 52 per 1000 Soweto children. The auscultatory features of a non-ejection systolic click and late systolic murmur were prevalent (13.9 per 1000) and had several epidemiological factors in common with R.H.D. A comprehensive preventative campaign is urgently needed in South Africa, directed at both primary and secondary prophylaxis of R.H.D. The socioeconomic status of the community must be improved if optimal prevention is to be achieved.

摘要

在约翰内斯堡西南镇区(索韦托)的托儿所和小学开展了一项调查,以确定黑人儿童风湿性心脏病(R.H.D.)的患病率。1972年5月至10月,10位心脏病专家对总共12050名黑人儿童进行了检查。R.H.D.的总体患病率为每1000人中有6.9例,七年级儿童的患病率最高,为每1000人中有19.2例。最高发病年龄为15 - 18岁,女性患病率高于男性,比例为1.6:1。患病率随着家庭规模的增大而上升。大多数儿童(92%)没有症状,82.5%的R.H.D.患儿是在学校调查期间首次被诊断出来的。最常见的瓣膜病变是二尖瓣反流,93%的患儿存在该病变,其中47.5%为孤立性病变。每1000名索韦托儿童中,有52人的咽喉部分离出了A群兰斯菲尔德β溶血性链球菌。非喷射性收缩期喀喇音和收缩晚期杂音的听诊特征很常见(每1000人中有13.9例),并且与R.H.D.有几个共同的流行病学因素。南非迫切需要开展一项全面的预防运动,针对R.H.D.的一级和二级预防。如果要实现最佳预防效果,就必须改善社区的社会经济状况。

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