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宫颈涂片进行产前性别检测:利用Y体荧光法取得成功结果。

Prenatal sex detection with endocervical smears: successful results utilizing Y-bodyfluoroscence.

作者信息

Rhine S A, Cain J L, Cleary R E, Palmer C G, Thompson J F

出版信息

Am J Obstet Gynecol. 1975 May;122(2):155-60. doi: 10.1016/s0002-9378(16)33486-x.

Abstract

Highly equivocal results, regarding procedures for the prenatal detection of fetal sexls found in the endocervix, are reported in the literature dating from 1971. The far-reaching genetic and obstetric implications of such procedures led us to investigate endocervical smears from 36 patients (taken during all three trimesters) and study the validity and practicality of this test. Fetal sex was correctly predicted in 31 of 36cases and all 18 male predictions delivered males. In addition, many previously reported and newly found sources of error were encountered and evaluated. It is concludedthat there are indeed cells of fetal origin being shed into the endocervix and they canbe used as a reliable indicator of fetal sex in all three trimesters.

摘要

1971年以来的文献报道了关于宫颈内胎儿性别产前检测程序的高度模棱两可的结果。此类程序深远的遗传学和产科意义促使我们对36例患者(在所有三个孕期采集)的宫颈涂片进行研究,并探讨该检测的有效性和实用性。36例中有31例正确预测了胎儿性别,所有18例预测为男性的孕妇均分娩出男性胎儿。此外,我们还遇到并评估了许多先前报道和新发现的误差来源。结论是,确实有胎儿来源的细胞脱落至宫颈内,并且它们可作为所有三个孕期胎儿性别的可靠指标。

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