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从宫颈检测胎儿Y特异性DNA。

Detection of fetal Y-specific DNA from the cervix.

作者信息

Fung H Y, Wong Y F, Haines C J

机构信息

Department of Obstetrics and Gynecology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin.

出版信息

Acta Obstet Gynecol Scand. 1995 Apr;74(4):248-50. doi: 10.3109/00016349509024443.

Abstract

Detection of fetal Y-specific DNA by polymerase chain reaction was performed on cervical samplings obtained from 24 patients who underwent first trimester suction termination of pregnancy. The results were compared with the fetal gender determined by Y-sequence polymerase chain reaction on the fetal parts. Fourteen male pregnancies were identified. Correct predictions were made in two (14.3%) from the cervical swabs and three (21.4%) from the trans-cervical samplings. The failure of isolation of fetal cells from the cervix was not related to the gestation of sampling.

摘要

对24例在孕早期行人工流产终止妊娠的患者宫颈样本进行聚合酶链反应检测胎儿Y特异性DNA。将结果与通过胎儿组织的Y序列聚合酶链反应确定的胎儿性别进行比较。共识别出14例男性胎儿妊娠。宫颈拭子中有2例(14.3%)、经宫颈采样中有3例(21.4%)做出了正确预测。未能从宫颈中分离出胎儿细胞与采样时的孕周无关。

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