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Studies of catalysis by acetylcholinesterase. Synergistic effects of inhibitors during the hydrolysis of acetic acid esters.

作者信息

Rosenberry T L, Bernhard S A

出版信息

Biochemistry. 1972 Nov 7;11(23):4308-21. doi: 10.1021/bi00773a018.

DOI:10.1021/bi00773a018
PMID:5079901
Abstract
摘要

相似文献

1
Studies of catalysis by acetylcholinesterase. Synergistic effects of inhibitors during the hydrolysis of acetic acid esters.乙酰胆碱酯酶催化作用的研究。乙酸酯水解过程中抑制剂的协同效应。
Biochemistry. 1972 Nov 7;11(23):4308-21. doi: 10.1021/bi00773a018.
2
Ligand binding properties of acetylcholinesterase determined with fluorescent probes.用荧光探针测定乙酰胆碱酯酶的配体结合特性。
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3
The reaction of tris-(choline chloride) phosphate with eel cholinesterase.磷酸三(氯化胆碱)与鳗鱼胆碱酯酶的反应。
Biochim Biophys Acta. 1972 Sep 19;284(1):157-63. doi: 10.1016/0005-2744(72)90054-x.
4
The reaction of acetylcholinesterase with methanesulfonyl esters of quaternary quinolinium compounds.乙酰胆碱酯酶与季铵喹啉化合物甲磺酸酯的反应。
Biochem Pharmacol. 1969 Feb;18(2):269-78. doi: 10.1016/0006-2952(69)90204-4.
5
Relative binding sites of pharmacologically active ligands on bovine erythrocyte acetylcholinesterase.
Mol Pharmacol. 1972 Jan;8(1):41-9.
6
Identification of a modifier site on acetylcholinesterase with affinity for d-tubocurarine.
Biochem Biophys Res Commun. 1972 Aug 7;48(3):559-64. doi: 10.1016/0006-291x(72)90384-1.
7
Studies of catalysis by acetylcholinesterase. I. Fluorescent titration with a carbamoylating agent.乙酰胆碱酯酶催化作用的研究。I. 用氨基甲酰化剂进行荧光滴定。
Biochemistry. 1971 Oct 26;10(22):4114-20. doi: 10.1021/bi00798a016.
8
Interaction between bisquaternary ammonium ligands and acetylcholinesterase: complex formation studied by fluorescence quenching.
Mol Pharmacol. 1974 Jan;10(1):93-107.
9
Effects of edrophonium, eserine, decamethonium, d-tubocurarine, and gallamine on the kinetics of membrane-bound and solubilized eel acetylcholinesterase.腾喜龙、毒扁豆碱、十烃季铵、d-筒箭毒碱和加拉明对膜结合型和可溶性鳗鱼乙酰胆碱酯酶动力学的影响。
Mol Pharmacol. 1975 Nov;11(6):722-34.
10
[Separation of the receptor protein of acetylcholine and acetylcholinesterase].[乙酰胆碱受体蛋白与乙酰胆碱酯酶的分离]
C R Acad Hebd Seances Acad Sci D. 1971 Jan 4;272(1):117-20.

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Rate-limiting step in the decarbamoylation of acetylcholinesterases with large carbamoyl groups.具有大的氨基甲酰基的乙酰胆碱酯酶脱氨基甲酰化的限速步骤。
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2
Decarbamoylation of acetylcholinesterases is markedly slowed as carbamoyl groups increase in size.乙酰胆碱酯酶的脱酰胺作用随着碳酰胺基团的增大而明显减慢。
Arch Biochem Biophys. 2018 Oct 1;655:67-74. doi: 10.1016/j.abb.2018.08.006. Epub 2018 Aug 9.
3
Strategies to resolve the catalytic mechanism of acetylcholinesterase.
解决乙酰胆碱酯酶催化机制的策略。
J Mol Neurosci. 2010 Jan;40(1-2):32-9. doi: 10.1007/s12031-009-9250-3.
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Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter.使用硫黄素T作为偶联荧光报告分子分析卡巴胆碱与乙酰胆碱酯酶的反应。
Biochemistry. 2008 Dec 9;47(49):13056-63. doi: 10.1021/bi8015197.
5
Monitoring the reaction of carbachol with acetylcholinesterase by thioflavin T fluorescence and acetylthiocholine hydrolysis.通过硫黄素T荧光法和乙酰硫代胆碱水解法监测卡巴胆碱与乙酰胆碱酯酶的反应。
Chem Biol Interact. 2008 Sep 25;175(1-3):235-41. doi: 10.1016/j.cbi.2008.06.002. Epub 2008 Jun 17.
6
Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding.碳酸酐酶作为蛋白质及蛋白质-配体结合的生物物理和物理有机研究模型。
Chem Rev. 2008 Mar;108(3):946-1051. doi: 10.1021/cr050262p.
7
Acetylcholinesterase kinetics.乙酰胆碱酯酶动力学
Biophys Struct Mech. 1981;8(1-2):45-59. doi: 10.1007/BF01047105.
8
A steady-state kinetic model of butyrylcholinesterase from horse plasma.马血浆丁酰胆碱酯酶的稳态动力学模型。
Biochem J. 1974 Sep;141(3):825-34. doi: 10.1042/bj1410825.
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Sequential model to describe the nicotinic synaptic current.描述烟碱型突触电流的序列模型。
Biophys J. 1989 May;55(5):875-84. doi: 10.1016/S0006-3495(89)82886-3.
10
Differential effects of ethanol on membrane-bound and soluble acetylcholinesterase from sarcoplasmic reticulum membranes.乙醇对肌浆网膜结合型和可溶性乙酰胆碱酯酶的不同作用
Neurochem Res. 1992 Jul;17(7):717-22. doi: 10.1007/BF00968011.