Significance of azathioprine metabolites.
作者信息
Elion G B
出版信息
Proc R Soc Med. 1972 Mar;65(3):257-60. doi: 10.1177/003591577206500315.
Abstract
摘要
相似文献
1
Significance of azathioprine metabolites.
Proc R Soc Med. 1972 Mar;65(3):257-60. doi: 10.1177/003591577206500315.
2
Serum immunosuppressive activity of azathioprine in normal subjects and patients with liver diseases.硫唑嘌呤在正常受试者和肝病患者中的血清免疫抑制活性。
Proc R Soc Med. 1972 Mar;65(3):260-3. doi: 10.1177/003591577206500316.
3
HPLC analysis of azathioprine metabolites in red blood cells, plasma and urine in renal transplant recipients.肾移植受者红细胞、血浆和尿液中硫唑嘌呤代谢物的高效液相色谱分析。
Int J Clin Pharmacol Ther. 1995 Dec;33(12):639-45.
4
[Determination of active metabolites of immunosuppressive agents in the serum. Application to azathioprine].
Nouv Presse Med. 1972 Oct 7;1(35):2293-8.
5
Demonstration of enzymatic activity converting azathioprine to 6-mercaptopurine.将硫唑嘌呤转化为6-巯基嘌呤的酶活性的证明。
Acta Med Okayama. 1978 Jul;32(3):173-9.
6
The metabolic fate of the methylnitroimidazole moiety of azathioprine in the rat.
J Pharmacol Exp Ther. 1973 Dec;187(3):588-601.
7
Pharmacokinetics of azathioprine and 6-mercaptopurine: methodological aspects and preliminary results in uremic patients.硫唑嘌呤和6-巯基嘌呤的药代动力学：方法学方面及尿毒症患者的初步结果
Scand J Urol Nephrol Suppl. 1981;64:213-9.
8
Conversion of azathioprine into mercaptopurine and mercaptoimidazole derivatives in vitro and during immunosuppressive therapy.
Aust J Exp Biol Med Sci. 1967 Dec;45(6):681-91. doi: 10.1038/icb.1967.68.
9
10
Inhibition of hepatic metabolism of azathioprine in vivo.
Gastroenterology. 1978 Jan;74(1):90-2.
引用本文的文献
1
Combination treatment with 6-mercaptopurine and allopurinol in HepG2 and HEK293 cells - Effects on gene expression levels and thiopurine metabolism.6-巯基嘌呤与别嘌呤醇联合处理HepG2和HEK293细胞——对基因表达水平和硫嘌呤代谢的影响
PLoS One. 2017 Mar 9;12(3):e0173825. doi: 10.1371/journal.pone.0173825. eCollection 2017.
2
Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients.基于模型的体外毒性数据情境化定量预测患者体内药物反应。
Arch Toxicol. 2017 Feb;91(2):865-883. doi: 10.1007/s00204-016-1723-x. Epub 2016 May 9.
3
Azathioprine in autologous serum skin test positive chronic urticaria: A case-control study in a tertiary care hospital of eastern India.硫唑嘌呤在自体血清皮肤试验阳性的慢性荨麻疹中的应用：印度东部一家三级医院的病例对照研究
Indian Dermatol Online J. 2015 May-Jun;6(3):185-8. doi: 10.4103/2229-5178.156391.
4
Thiopurine treatment in inflammatory bowel disease: clinical pharmacology and implication of pharmacogenetically guided dosing.硫唑嘌呤在炎症性肠病中的治疗：临床药理学及药物基因组学指导给药的意义
Clin Pharmacokinet. 2007;46(3):187-208. doi: 10.2165/00003088-200746030-00001.
5
Pharmacologically active metabolites of drugs and other foreign compounds. Clinical, pharmacological, therapeutic and toxicological considerations.药物及其他外来化合物的药理活性代谢产物。临床、药理、治疗及毒理学考量。
Drugs. 1982 Dec;24(6):519-42. doi: 10.2165/00003495-198224060-00003.
6
Immunosuppressive activity in patients with active chronic hepatitis and primary biliary cirrhosis treated with azathioprine.接受硫唑嘌呤治疗的活动性慢性肝炎和原发性胆汁性肝硬化患者的免疫抑制活性。
Gut. 1972 Nov;13(11):907-14. doi: 10.1136/gut.13.11.907.
7
Liver disease in childhood: principles of management.儿童肝病：管理原则
Postgrad Med J. 1974 Jun;50(584):381-5. doi: 10.1136/pgmj.50.584.381.
8
Induction of uterine hemangioendothelioma and lymphoma in (C57BL/6N x C3H/2N)F1 mice by oral administration of azathioprine.通过口服硫唑嘌呤在（C57BL/6N×C3H/2N）F1小鼠中诱导子宫血管内皮瘤和淋巴瘤。
Jpn J Cancer Res. 1989 May;80(5):419-23. doi: 10.1111/j.1349-7006.1989.tb02330.x.
9
The clinical pharmacology of 6-mercaptopurine.6-巯基嘌呤的临床药理学。
Eur J Clin Pharmacol. 1992;43(4):329-39. doi: 10.1007/BF02220605.
10
Problems with immunosuppressive agents in renal disease.肾病中免疫抑制剂的问题。
J Clin Pathol Suppl (R Coll Pathol). 1975;9:24-35.
本文引用的文献
1
The fate of 6-mercaptopurine in man.6-巯基嘌呤在人体内的代谢情况。
Ann N Y Acad Sci. 1954 Dec 6;60(2):304-14. doi: 10.1111/j.1749-6632.1954.tb40021.x.
2
The fate of 6-mercaptopurine in mice.6-巯基嘌呤在小鼠体内的代谢情况
Ann N Y Acad Sci. 1954 Dec 6;60(2):297-303. doi: 10.1111/j.1749-6632.1954.tb40020.x.
3
RELATIONSHIP BETWEEN METABOLIC FATES AND ANTITUMOR ACTIVITIES OF THIOPURINES.硫嘌呤的代谢命运与抗肿瘤活性之间的关系
Cancer Res. 1963 Sep;23:1207-17.
4
Experimental, clinical, and metabolic studies of thiopurines.硫唑嘌呤的实验、临床及代谢研究
Cancer Chemother Rep. 1962 Feb;16:197-202.
5
In vitro evaluation of immunosuppressive drugs.免疫抑制药物的体外评估。
Nature. 1969 Jun 7;222(5197):998-9. doi: 10.1038/222998a0.
6
Symposium on immunosuppressive drugs. Biochemistry and pharmacology of purine analogues.免疫抑制药物研讨会。嘌呤类似物的生物化学与药理学
Fed Proc. 1967 May-Jun;26(3):898-904.
7
[Studies on the metabolism of azathioprine].[硫唑嘌呤的代谢研究]
C R Acad Hebd Seances Acad Sci D. 1970 Jul 27;271(4):453-6.
8
Serum immunosuppressive activity due to azathioprine and its relation to hepatic function after liver transplantation.
Lancet. 1970 Jun 6;1(7658):1196-9. doi: 10.1016/s0140-6736(70)91786-1.
Zotero 插件