Miller D A, Miller O J
Science. 1972 Dec 1;178(4064):949-55. doi: 10.1126/science.178.4064.949.
Chromosome banding techniques have permitted the identification of every normal chromosome in the mouse, Mus musculus, and the demonstration of strain differences. By identifying the chromosomes involved in a series of translocations, it has been possible to assign 14 of the 19 known linkage groups to 14 different chromosomes. These powerful cytological methods promise to revolutionize cytogenetic studies in higher organisms.
染色体显带技术已能够识别小家鼠(Mus musculus)的每一条正常染色体,并证明了品系差异。通过识别一系列易位中涉及的染色体,已将19个已知连锁群中的14个定位到14条不同的染色体上。这些强大的细胞学方法有望彻底改变高等生物的细胞遗传学研究。