大鼠离体心室实验性诱发的自动节律
Experimentally induced automatism in rat isolated ventricle.
作者信息
Garcia de Jalón P D, Moratinos J P, Serrano J S
出版信息
Br J Pharmacol. 1972 Sep;46(1):167-9. doi: 10.1111/j.1476-5381.1972.tb06859.x.
Abstract
Exposure to isoprenaline plus electrical stimulation of the isolated right ventricle of the rat produces stable ventricular automatic activity of various types. The incidence of these different types of ventricular arrhythmia is tabulated and analysed. The technique allows the antiarrhythmic activity of drugs to be studied at cellular level where extracardiac factors are excluded.
摘要
将大鼠离体右心室暴露于异丙肾上腺素并进行电刺激可产生各种类型的稳定心室自动活动。将这些不同类型室性心律失常的发生率制成表格并进行分析。该技术可在排除心外因素的细胞水平研究药物的抗心律失常活性。
相似文献
1
Experimentally induced automatism in rat isolated ventricle.大鼠离体心室实验性诱发的自动节律
Br J Pharmacol. 1972 Sep;46(1):167-9. doi: 10.1111/j.1476-5381.1972.tb06859.x.
2
Depression of automatism of potential cardiac pacemakers and of Luciani periods in hypoxia.
Bull Exp Biol Med. 1974 Dec;77(6):601-3. doi: 10.1007/BF00789975.
3
[Cellular factors of ventricular electrical desynchronization. Study on the isolated rabbit heart in conditions of normal perfusion and partial depolarization].
J Physiol (Paris). 1969 Jul-Aug;61(4):277-303.
4
Isoprenaline Impairs Contractile Function of Ventricular Myocardium in Common Frog (Rana temporaria).
Bull Exp Biol Med. 2018 Sep;165(5):606-609. doi: 10.1007/s10517-018-4223-6. Epub 2018 Sep 17.
5
[Reduced sensitivity of the heart ventricle of obese Zucker rats to isoprenaline].
C R Acad Sci III. 1988;306(4):153-6.
6
7
8
Electrophysiological basis for the enhanced cardiac arrhythmogenic effect of isoprenaline in aged spontaneously hypertensive rats.异丙肾上腺素对老年自发性高血压大鼠心律失常作用增强的电生理基础。
J Mol Cell Cardiol. 1994 Jul;26(7):849-60. doi: 10.1006/jmcc.1994.1102.
9
Ranolazine reduces remodeling of the right ventricle and provoked arrhythmias in rats with pulmonary hypertension.雷诺嗪可减少肺动脉高压大鼠右心室的重塑并诱发心律失常。
J Pharmacol Exp Ther. 2015 Jun;353(3):480-9. doi: 10.1124/jpet.114.221861. Epub 2015 Mar 13.
引用本文的文献
1
Simultaneous measurement of atrial and ventricular pacemaker activity.心房和心室起搏器活动的同步测量。
Br J Pharmacol. 1973 Apr;47(4):843-6. doi: 10.1111/j.1476-5381.1973.tb08212.x.
2
Interaction of cocaine and bunaphtide on the 3H-norepinephrine uptake mechanism on isolated left atrium of guinea-pig.
Experientia. 1978 Jun 15;34(6):770. doi: 10.1007/BF01947316.
本文引用的文献
1
A COMPUTER MODEL OF ATRIAL FIBRILLATION.心房颤动的计算机模型
Am Heart J. 1964 Feb;67:200-20. doi: 10.1016/0002-8703(64)90371-0.
2
The cause of fibrillation.纤维性颤动的病因。
Can Med Assoc J. 1961 Mar 25;84(12):625-7.
3
The actions of digitalis leaf preparations and of cardiac glycosides on the isolated right ventricle of the guinea pig.洋地黄叶制剂和强心苷对豚鼠离体右心室的作用。
J Pharm Pharmacol. 1958 Dec;10(12):741-54. doi: 10.1111/j.2042-7158.1958.tb10368.x.
4
Mechanism of flutter and fibrillation.扑动与颤动的机制。
AMA Arch Intern Med. 1953 Mar;91(3):333-52. doi: 10.1001/archinte.1953.00240150052007.
Zotero 插件