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由等量致红斑剂量的紫外线A、紫外线B、紫外线C以及紫外线A与补骨脂素联合作用于皮肤所产生的组织学变化。

Histological changes produced in skin by equally erythemogenic doses of UV-A, UV-B, UV-C and UV-A with psoralens.

作者信息

Rosario R, Mark G J, Parrish J A, Mihm M C

出版信息

Br J Dermatol. 1979 Sep;101(3):299-308. doi: 10.1111/j.1365-2133.1979.tb05623.x.

DOI:10.1111/j.1365-2133.1979.tb05623.x
PMID:508596
Abstract

The sequential light microscopic histological changes produced in human skin by a single exposure of UV-A, UV-B, UV-C and oral 8-methoxypsoralen plus UV-A (PUVA) causing approximately equal degress of delayed erythema response, have been evaluated. UV-C and UV-B affect the epidermis to a greater degree than UV-A, while UV-A affects the dermis to a greater degree than UV-B and UV-C. PUVA has prominent effects on both epidermis and dermis, differing in degree from those changes induced by UV-A, UV-B, and UV-C and are longer lasting. The sequence of histological changes following UV exposure is completed more rapidly after exposure to shorter UV wavelengths.

摘要

已经评估了单次暴露于紫外线A(UV-A)、紫外线B(UV-B)、紫外线C(UV-C)以及口服8-甲氧基补骨脂素加紫外线A(PUVA)后,在人体皮肤中产生的连续光学显微镜组织学变化,这些暴露引起的延迟红斑反应程度大致相等。UV-C和UV-B对表皮的影响程度大于UV-A,而UV-A对真皮的影响程度大于UV-B和UV-C。PUVA对表皮和真皮都有显著影响,其程度与UV-A、UV-B和UV-C引起的变化不同,且持续时间更长。暴露于较短紫外线波长后,紫外线暴露后的组织学变化序列完成得更快。

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Histological changes produced in skin by equally erythemogenic doses of UV-A, UV-B, UV-C and UV-A with psoralens.由等量致红斑剂量的紫外线A、紫外线B、紫外线C以及紫外线A与补骨脂素联合作用于皮肤所产生的组织学变化。
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