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慢性胃炎、酒精与非溃疡性消化不良。

Chronic gastritis, alcohol, and non-ulcer dyspepsia.

作者信息

Roberts D M

出版信息

Gut. 1972 Oct;13(10):768-74. doi: 10.1136/gut.13.10.768.

DOI:10.1136/gut.13.10.768
PMID:5087067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1412478/
Abstract

An investigation of 102 men comprising alcoholics, patients with non-ulcer dyspepsia, and healthy controls is reported. It demonstrates that alcohol is a cause of chronic gastritis and the severity of the mucosal lesion is directly related to the duration of excess drinking. Contrary to popular belief, chronic gastritis does not give rise to symptoms. The effect of alcohol on the gastric mucosa is a direct one and is not mediated by malnutrition, hepatic damage, intestinal malabsorption, anaemia, ascorbic acid deficiency, or any disturbance in immune tolerance. The natural history of chronic gastritis is described, involving an initial hypertrophy and hyperfunction of the gastric mucosa, followed by atrophy and hypofunction. Cigarette smoking is confirmed as another cause of chronic gastritis. The non-ulcer dyspepsia syndrome is unrelated to chronic gastritis.

摘要

报告了一项对102名男性的调查，这些男性包括酗酒者、非溃疡性消化不良患者和健康对照者。研究表明，酒精是慢性胃炎的一个病因，黏膜病变的严重程度与过量饮酒的持续时间直接相关。与普遍看法相反，慢性胃炎不会引起症状。酒精对胃黏膜的作用是直接的，并非由营养不良、肝损伤、肠道吸收不良、贫血、抗坏血酸缺乏或免疫耐受的任何紊乱介导。描述了慢性胃炎的自然病程，包括最初胃黏膜的肥大和功能亢进，随后是萎缩和功能减退。吸烟被确认为慢性胃炎的另一个病因。非溃疡性消化不良综合征与慢性胃炎无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/e20dbc8927e4/gut00647-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/8ec46b9e4716/gut00647-0025-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/3e0628cda9d9/gut00647-0025-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/3ab86c0fc705/gut00647-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/0759209828c5/gut00647-0026-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/4d62bc91f29a/gut00647-0026-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/e20dbc8927e4/gut00647-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/8ec46b9e4716/gut00647-0025-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/3e0628cda9d9/gut00647-0025-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/3ab86c0fc705/gut00647-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/0759209828c5/gut00647-0026-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/4d62bc91f29a/gut00647-0026-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1c/1412478/e20dbc8927e4/gut00647-0027-a.jpg

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2
THE RADIOLOGICAL DIAGNOSIS OF GASTRIC ATROPHY.胃萎缩的放射学诊断
Br J Radiol. 1963 Aug;36:578-82. doi: 10.1259/0007-1285-36-428-578.
3
A study of x-ray negative dyspepsia with reference to histologic changes in the gastric mucosa.一项关于X线阴性消化不良与胃黏膜组织学变化关系的研究。
发酵大豆（（L.）Merr.）对乙醇/盐酸诱导的大鼠胃损伤的胃保护作用。
Nutrients. 2022 May 16;14(10):2079. doi: 10.3390/nu14102079.
4
Portal Hypertensive Gastropathy in Liver Cirrhosis: Prevalence, Natural History, and Risk Factors.肝硬化门静脉高压性胃病：患病率、自然史和危险因素。
Intern Med. 2022;61(5):605-613. doi: 10.2169/internalmedicine.7943-21. Epub 2022 Mar 1.
5
Cannabinoid Hyperemesis Syndrome: A Case Report and Discussion Regarding Patients with Concurrent Disorders.大麻素呕吐综合征：一例并发疾病患者的病例报告及讨论
Can J Hosp Pharm. 2020 Fall;73(4):290-293. Epub 2020 Oct 1.
6
Alcoholic disease: liver and beyond.酒精性疾病：肝脏及其他器官
World J Gastroenterol. 2014 Oct 28;20(40):14652-9. doi: 10.3748/wjg.v20.i40.14652.
7
Alcohol abuse: critical pathophysiological processes and contribution to disease burden.酒精滥用：关键的病理生理过程及其对疾病负担的影响
Physiology (Bethesda). 2014 May;29(3):203-15. doi: 10.1152/physiol.00055.2013.
8
From ischochymia to gastroparesis: proposed mechanisms and preferred management of dyspepsia over the centuries.从消化不良到胃轻瘫：几个世纪以来消化不良的发病机制和治疗方法。
Dig Dis Sci. 2014 Jun;59(6):1088-98. doi: 10.1007/s10620-014-3144-0. Epub 2014 Apr 9.
9
A randomised controlled trial of structured nurse-led outpatient clinic follow-up for dyspeptic patients after direct access gastroscopy.直接就诊胃镜检查后消化不良患者由护士主导的结构化门诊随访随机对照试验。
BMC Gastroenterol. 2009 Feb 6;9:12. doi: 10.1186/1471-230X-9-12.
10
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J Clin Pathol. 1981 Jul;34(7):744-8. doi: 10.1136/jcp.34.7.744.
Gastroenterology. 1957 Feb;32(2):313-24.
4
Effects of alcohol on gastric mucosa.酒精对胃黏膜的影响。
Br Med J. 1956 Feb 4;1(4961):256-9. doi: 10.1136/bmj.1.4961.256.
5
Gastric biopsy; a study of 1,000 consecutive successful gastric biopsies.胃活检；对1000例连续成功的胃活检病例的研究。
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8
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