Andersson N, Griffiths H, Murphy J, Roll J, Serenyi A, Swann I, Cockcroft A, Myers J, St Leger A
Br Med J. 1979 Sep 22;2(6192):697-8. doi: 10.1136/bmj.2.6192.697.
A family history of appendicectomy was sought in two groups of children admitted to Llandough Hospital over sixteen months. The study group consisted of 29 children with histologically confirmed acute appendicitis, while the control group consisted of 29 children admitted for reasons unrelated to abdominal pain. A history of appendicectomy was elicited in first-degree relatives--that is, siblings and parents of 20 of the children in the study group and of four of the controls--a statistically significant difference. The results obtained from this study suggest that a familial predisposition to appendicitis exists.
在16个月期间，对两组入住兰多医院的儿童进行了阑尾切除术家族史调查。研究组由29名经组织学确诊为急性阑尾炎的儿童组成，而对照组由29名因与腹痛无关的原因入院的儿童组成。在一级亲属（即研究组中20名儿童以及对照组中4名儿童的兄弟姐妹和父母）中发现了阑尾切除术史，这一差异具有统计学意义。这项研究的结果表明，阑尾炎存在家族易感性。
