Graham N G, De Dombal F T, Goligher J C
Br Med J. 1971 Jun 26;2(5764):746-8. doi: 10.1136/bmj.2.5764.746.
A series of observer variation studies in a small group of patients suffering from severe acute ulcerative colitis is reported. Seventy-two separate assessments of the patients' physical signs and clinical progress were made by three independent observers.The results of this investigation suggest that there is difficulty in eliciting general physical signs such as anaemia or dehydration in these patients. By contrast, local abdominal signs such as tenderness and distension were relatively reliably elicited. The results also suggest that there are considerable problems in evaluating these clinical signs in terms of the patient's immediate subsequent progress.
报告了对一小群重症急性溃疡性结肠炎患者进行的一系列观察者变异研究。三位独立观察者对患者的体征和临床进展进行了72次单独评估。这项调查结果表明，在这些患者中很难引出诸如贫血或脱水等一般体征。相比之下，诸如压痛和腹胀等局部腹部体征相对较易引出。结果还表明，根据患者随后的直接进展来评估这些临床体征存在相当大的问题。
