泼尼松龙诱导的大鼠小肠结构和肽酶活性变化
Changes in structure and peptidase activity of rat small intestine induced by prednisolone.
作者信息
Wall A J, Peters T J
出版信息
Gut. 1971 Jun;12(6):445-8. doi: 10.1136/gut.12.6.445.
Abstract
Chronic dietary administration of prednisolone to the adult rat caused alteration in morphology and enzyme activity of the small intestinal mucosa. Reduction of villous height, crypt depth, and surface epithelial cell height was accompanied by a significant increase in the specific activity of several jejunal peptidases.
摘要
对成年大鼠长期进行泼尼松龙饮食给药会导致小肠黏膜的形态和酶活性发生改变。绒毛高度、隐窝深度和表面上皮细胞高度降低的同时，空肠中几种肽酶的比活性显著增加。
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