Timofeeva N M, Gordova L A, Egorova V V, Iezuitova N N, Nikitina A A, Pashkin V A, Rydin I S, Starchenko S V, Sheptitskiĭ V A
Fiziol Zh Im I M Sechenova. 1996 Mar;82(3):36-45.
At different times after the transposition of the jejunum and ileum of rats bidirectional changes in the mass and activity of digestive enzymes were observed not only in the epithelial but also in the subepithelial layers of various parts of the small intestine and in the duodenal mucosa. The greatest increase in the mucosal mass was revealed in the duodenum. The activity of membrane enzymes changed insignificantly in the epithelial and subepithelial layers. The activity of cytosolic peptidases was increased to the greatest extent in the subepithelial layers of the small intestine, especially at the early terms after surgical interventions. It is concluded, that the enzyme systems (particularly, peptidase) of the subepithelial layers of the small intestine are an integral part of the enzymatic barrier and perform an important protective function.
