γ-D副蛋白血症——16例报告

Gamma-D paraproteinemia - a report of 16 cases.

作者信息

Schneider W, Fröhlich C, Glassner K, McCarty L J

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1975;102(1):13-9.

Abstract

Paraproteins of the gammaD class are very rare, being found in only 0.3% to 3.0% of the cases of all paraproteinemias. They are difficult to detect and therefore sometimes not found or mis-diagnosed. In the 6500 cases of paraproteinemia we have diagnosed over the last eight years, 16 of them have been gammaD. Consistent with the reports of other gammaD paraproteinemias most of these 16 cases were of type L (13), most patients were male (11), the average age (55), was younger than that of patients suffering from other paraproteinemias, and in all cases the disease followed a rapidly malignant course.

摘要

γD类副蛋白非常罕见，仅在所有副蛋白血症病例的0.3%至3.0%中被发现。它们很难检测到，因此有时未被发现或被误诊。在过去八年我们诊断的6500例副蛋白血症病例中，有16例为γD型。与其他γD型副蛋白血症的报告一致，这16例病例中的大多数为L型（13例），大多数患者为男性（11例），平均年龄（55岁）比其他副蛋白血症患者的年龄小，并且在所有病例中疾病都呈快速恶性病程。