Seiga K, Yamaji K
Appl Microbiol. 1971 Jun;21(6):986-9. doi: 10.1128/am.21.6.986-989.1971.
Copiamycin, an antibiotic agent, has shown in vitro activity against Candida albicans, Torulopsis glabrata, and Trichomonas vaginalis. Local administration of copiamycin to mice inoculated intraperitoneally with protozoa reduced the per cent of infection as measured by decreased abscess formation. This antibiotic has had little effect on the glucose oxidation by protozoa. Its action on anaerobic glucose metabolism in these organisms was equal to that of aminitrozole and azalomycin F. From these results we conclude that copiamycin is an effective antifungal and antitrichomonal agent equivalent in activity to azalomycin F.
可匹霉素是一种抗生素，已显示出对白色念珠菌、光滑球拟酵母菌和阴道毛滴虫的体外活性。给经腹腔接种原虫的小鼠局部施用可匹霉素，通过减少脓肿形成来衡量，可降低感染百分比。这种抗生素对原虫的葡萄糖氧化几乎没有影响。它对这些生物体厌氧葡萄糖代谢的作用与氨硝噻唑和阿扎霉素F相同。从这些结果我们得出结论，可匹霉素是一种有效的抗真菌和抗滴虫剂，其活性与阿扎霉素F相当。
