[Plasma concentration of PGE2, PGA2 and PGF2 alpha in the course of pregnancy (author's transl)].

Plasma levels of PGE2, PGA2 and PGF2 alpha were determined by radioimmunoassay in maternal cubital vein blood of 210 women and once during pregnancy. In the course of pregnancy plasma levels of these prostaglandins varied considerably: 0,09-1,83 ng PGE2/ml, 0,12-2,8 ng PGA2/ml and 0,04-0,5 ng PGF2 alpha/ml. At term (40 and 41th week) prostaglandin levels were found to be low and within a range of: 0,15-0,25 ng PGE2/ml; 0,12-0,23 ng PGA2/ml and 0,2-0,3 ng PGF2 alpha/ml. Determination of prostaglandin levels in numerous samples from different women during pregnancy did not show continuous changes nor in the pattern of the distribution of PGE2, PGA2 and PGF2 alpha.