类鼻疽假单胞菌菌株对利福平的体外敏感性
In vitro susceptibility of strains of Pseudomonas pseudomallei to rifampin.
作者信息
Alexander A D, Williams L C
出版信息
Appl Microbiol. 1971 Jul;22(1):11-2. doi: 10.1128/am.22.1.11-12.1971.
Abstract
Reported high activity of rifampin for Pseudomonas pseudomallei could not be verified by extensive in vitro tests conducted with 31 recently isolated strains. Minimal inhibitory concentrations of rifampin were 25 mug/ml for three strains and greater than 25 mug/ml for 28 strains. Rifampin had relatively poor in vitro activity when compared with tetracycline drugs and chloramphenicol antibiotics now commonly used for treating melioidosis.
摘要
据报道，利福平对类鼻疽杆菌具有高活性，但对最近分离出的31株菌株进行的广泛体外试验未能证实这一点。利福平对3株菌株的最低抑菌浓度为25微克/毫升，对28株菌株则大于25微克/毫升。与目前常用于治疗类鼻疽病的四环素类药物和氯霉素类抗生素相比，利福平的体外活性相对较差。
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本文引用的文献
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Afebrile cases of melioidosis.类鼻疽无发热病例。
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The control of experimental infection in mice produced by Pseudomonas pseudomallei.由类鼻疽假单胞菌引起的小鼠实验性感染的控制
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Serial dilution antibiotic sensitivity testing with the microtitrator system.使用微量滴定仪系统进行系列稀释抗生素敏感性测试。
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Pseudomonas pseudomallei: susceptibility to chemotherapeutic agents.类鼻疽杆菌：对化疗药物的敏感性
J Infect Dis. 1970 Feb;121(2):95-102. doi: 10.1093/infdis/121.2.95.
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Susceptibility in vitro and in vivo of Pseudomonas pseudomallei to rifampin and tetracyclines.类鼻疽杆菌对利福平和四环素的体外及体内敏感性
Appl Microbiol. 1971 Jul;22(1):13-6. doi: 10.1128/am.22.1.13-16.1971.
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