Alexander A D, Williams L C
Appl Microbiol. 1971 Jul;22(1):11-2. doi: 10.1128/am.22.1.11-12.1971.
Reported high activity of rifampin for Pseudomonas pseudomallei could not be verified by extensive in vitro tests conducted with 31 recently isolated strains. Minimal inhibitory concentrations of rifampin were 25 mug/ml for three strains and greater than 25 mug/ml for 28 strains. Rifampin had relatively poor in vitro activity when compared with tetracycline drugs and chloramphenicol antibiotics now commonly used for treating melioidosis.
据报道，利福平对类鼻疽杆菌具有高活性，但对最近分离出的31株菌株进行的广泛体外试验未能证实这一点。利福平对3株菌株的最低抑菌浓度为25微克/毫升，对28株菌株则大于25微克/毫升。与目前常用于治疗类鼻疽病的四环素类药物和氯霉素类抗生素相比，利福平的体外活性相对较差。
