对57个信息充分的家族进行HLA - GLO连锁分析。

HLA-GLO linkage analysis in 57 informative families.

作者信息

Hansen H E, Eriksen B

出版信息

Hum Hered. 1979;29(6):355-60. doi: 10.1159/000153072.

Abstract

The HLA-GLO linkage relationship was investigated among 37 single backcross families with 97 children and 20 double intercross families with 51 children. For the total number of families the value Zmas = 14.600 for theta = 0.060 was found. A total of 11 cross-overs between HLA and GLO were found leading to a recombination fraction of 0.067. 221 unrelated haplotypes were examined for linkage disequilibrium between HLA and GLO, and no disequilibrium was found.

摘要

在37个有97名子女的单回交家庭和20个有51名子女的双互交家庭中研究了HLA - GLO的连锁关系。对于所有家庭，发现当θ = 0.060时，Zmas值为14.600。在HLA和GLO之间共发现11次交换，导致重组率为0.067。检查了221个无关单倍型中HLA和GLO之间的连锁不平衡，未发现不平衡。