连锁群GLO--Bf--HLA - B、C、A--PGM3.2的定位。分离分析。

Mapping of the linkage group GLO--Bf--HLA-B,C,A--PGM3. 2. Segregation analysis.

作者信息

Schunter F, Wernet P, Kömpf J, Bissbort S, Göhler F

出版信息

Hum Genet. 1978 Nov 16;44(3):321-31. doi: 10.1007/BF00394297.

Abstract

Segregation analysis of informative families for chromosome 6 markers confirmed the map order GLO--Bf--HLA-(B, C)--HLA-A, and, surprisingly, implies that PGM3 is more probably located on the HLA-A than on the HLA-B side of the linkage group. Therefore the map position of PGM3 should be reconsidered, i.e., more informative families should be tested for all the relevant marker loci available.

摘要

对6号染色体标记的信息丰富的家系进行分离分析，证实了图谱顺序为GLO--Bf--HLA-(B, C)--HLA-A，而且，令人惊讶的是，这意味着PGM3更有可能位于连锁群中HLA-A一侧而非HLA-B一侧。因此，PGM3的图谱位置应重新考虑，即应对所有可用的相关标记基因座检测更多信息丰富的家系。