Black M M, Bottoms E, Shuster S
Br Med J. 1971 Oct 16;4(5780):149-50. doi: 10.1136/bmj.4.5780.149.
The effects of stretching of the skin on its collagen content and thickness have been studied in a group of subjects with chronic obesity. Despite the increase in skin surface a normal skin thickness, collagen content, and density were maintained. It is concluded that the skin stretching induced by prolonged obesity led to hypertrophy of collagen and that this had maintained both skin thickness and collagen content. It is not known whether this is due to enhanced synthesis or decreased degradation.
在一组慢性肥胖受试者中，研究了皮肤拉伸对其胶原蛋白含量和厚度的影响。尽管皮肤表面积增加，但皮肤厚度、胶原蛋白含量和密度保持正常。得出的结论是，长期肥胖引起的皮肤拉伸导致胶原蛋白肥大，并且这维持了皮肤厚度和胶原蛋白含量。尚不清楚这是由于合成增强还是降解减少所致。
