人类意外过量使用阿米卡星：通过肾外透析进行紧急治疗。
Accidental amikacin overdose in man: emergency therapy by extrarenal dialysis.
作者信息
Flandrois J P, Bouletreau P, Auboyer C, Ducluzeau R, Muchada R, Etienne J
出版信息
Infection. 1979;7(4):190-1. doi: 10.1007/BF01640943.
PMID:511337
Abstract
Three accidental overdoses of amikacin (6, 6.5 and 8 times the normal dose) are reported. Emergency haemodialysis therapy was given and the serum levels monitored. No toxic effects were encountered. The need for such emergency haemodialysis seems to be limited to patients with impaired renal function or to cases where little time has elapsed between intake and detection of overdose.
摘要
据报道，发生了3起阿米卡星意外过量用药事件（分别为正常剂量的6倍、6.5倍和8倍）。给予了紧急血液透析治疗并监测血清水平。未出现毒性作用。这种紧急血液透析的必要性似乎仅限于肾功能受损的患者或摄入药物至发现过量之间时间间隔较短的情况。
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