Collins E, Turner G
Lancet. 1975 Aug 23;2(7930):335-8. doi: 10.1016/s0140-6736(75)92777-4.
6.6% of all Australian patients attending an antenatal clinic were found to be taking salicylate preparations regularly, most commonly in powder form and almost always as self-medication. In this group of salicylate takers there was an increased incidence of anaemia, anti-partum and post-partum haemorrhage, prolonged gestation, complicated deliveries, and perinatal mortality compared with non-takers. These findings suggest that regular salicylate consumption has detrimental effects in pregnancy. Routine antenatal urinary screening for salicylate in pregnancy is recommended.
在澳大利亚,6.6%前往产前诊所就诊的患者被发现经常服用水杨酸盐制剂,最常见的是粉末状,而且几乎都是自行用药。与未服用者相比,在这组服用水杨酸盐的人群中,贫血、产前和产后出血、孕期延长、分娩并发症以及围产期死亡率的发生率有所增加。这些发现表明,孕期经常服用水杨酸盐有不良影响。建议在孕期进行常规产前尿液水杨酸盐筛查。