肾上腺在大鼠缓激肽或硫酸纤维素所致白细胞增多症中的作用
Role of the adrenal gland in the leucocytosis caused by bradykinin or cellulose sulphate in the rat.
作者信息
Rothschild A M
出版信息
Br J Pharmacol. 1971 Aug;42(4):631-3. doi: 10.1111/j.1476-5381.1971.tb07147.x.
Abstract
Intravenous injections of bradykinin, cellulose sulphate (a kinin-releasing agent) or adrenaline cause rapid leucocytosis in the rat. The effect of the two former drugs is abolished by adrenalectomy, that of the latter is unaffected by this treatment. Bradykinin and agents capable of releasing it in plasma, may induce leucocytosis via adrenaline released from the adrenal gland.
摘要
静脉注射缓激肽、硫酸纤维素（一种激肽释放剂）或肾上腺素可使大鼠迅速出现白细胞增多。前两种药物的作用可被肾上腺切除所消除，而后者的作用不受该处理的影响。缓激肽以及能够在血浆中释放缓激肽的物质，可能通过肾上腺释放的肾上腺素诱导白细胞增多。
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